1D-MYO-INOSITOL-1,3,4-TRIPHOSPHATE, (NA+ SALT)
- Product Name
- 1D-MYO-INOSITOL-1,3,4-TRIPHOSPHATE, (NA+ SALT)
- Chemical Name
- 1D-MYO-INOSITOL-1,3,4-TRIPHOSPHATE, (NA+ SALT)
- Synonyms
- INS(2,4,5)P3 (NA+ SALT);INS(1,3,4)P3 (NA+ SALT);INS(1,3,4)IP3 (SODIUM SALT);D-MYO-INOSITOL-1,3,4-TRIPHOSPHATE SODIUM SALT;D-myo-Inositol-1,3,4-trisphosphate sodium salt;1D-MYO-INOSITOL-1,3,4-TRIPHOSPHATE, (NA+ SALT);1D-MYO-INOSITOL-2,4,5-TRISPHOSPHATE, (NA+ SALT);D-MYO-INOSITOL-1,3,4-TRIS(DIHYDROGEN PHOSPHATE), HEXASODIUM SALT
- CBNumber
- CB6755878
- Molecular Formula
- C6H9Na6O15P3
- Formula Weight
- 551.99
- MOL File
- Mol file
1D-MYO-INOSITOL-1,3,4-TRIPHOSPHATE, (NA+ SALT) Property
- solubility
- PBS pH 7.2: >50 mg/ml (from D-myo-Inositol
- form
- Lyophilized Powder
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- 60972
- Product name
- D-myo-Inositol-1,3,4-triphosphate (sodium salt)
- Packaging
- 100μg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 60972
- Product name
- D-myo-Inositol-1,3,4-triphosphate (sodium salt)
- Packaging
- 1mg
- Price
- $341
- Updated
- 2024/03/01
- Product number
- 60972
- Product name
- D-myo-Inositol-1,3,4-triphosphate (sodium salt)
- Packaging
- 500μg
- Price
- $193
- Updated
- 2024/03/01
- Product number
- 1733AH
- Product name
- d-Myo-inositol-1,3,4-triphosphate,sodiumsalt
- Packaging
- 5g
- Price
- $1072
- Updated
- 2021/12/16
1D-MYO-INOSITOL-1,3,4-TRIPHOSPHATE, (NA+ SALT) Chemical Properties,Usage,Production
Description
D-myo-Inositol-1,3,4-triphosphate (Ins(1,3,4)-P3) is one of several different inositol oligophosphate isomers implicated in signal transduction. Ins(1,3,4)-P3 acts through the inhibition of Ins(3,4,5,6)-P4 kinase activity to increase the cellular level of Ins(3,4,5,6)-P4 and thus inhibit calcium-activated chloride channels.1 The levels of Ins(1,3,4)-P3 are in turn regulated by the levels of cytosolic free calcium.2 The receptor-mediated activation of phospholipase C (PLC) can be seen as the initiating event in this cascade, since PLC generates Ins(1,4,5)-P3 which releases calcium from intracellular storage reservoirs, leading to a dramatic but transient increase in the cytosolic concentration of free calcium.3WARNING This product is not for human or veterinary use.
References
[1] X YANG. Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate.[J]. The Journal of Biological Chemistry, 1999, 274 27: 18973-18980. DOI: 10.1074/jbc.274.27.18973
[2] P D LEW. The role of cytosolic free calcium in the generation of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in HL-60 cells. Differential effects of chemotactic peptide receptor stimulation at distinct Ca2+ levels.[J]. The Journal of Biological Chemistry, 1986, 261 28: 13121-13127.
[3] Y YOSHIDA S I. Structure and function of inositol 1,4,5-trisphosphate receptor.[J]. Japanese journal of pharmacology, 1997, 74 2: 125-137. DOI: 10.1254/jjp.74.125
1D-MYO-INOSITOL-1,3,4-TRIPHOSPHATE, (NA+ SALT) Preparation Products And Raw materials
Raw materials
Preparation Products
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