ChemicalBook > CAS DataBase List > Hydroxymetronidazole

Hydroxymetronidazole

Product Name
Hydroxymetronidazole
CAS No.
4812-40-2
Chemical Name
Hydroxymetronidazole
Synonyms
MNZOH;METRONIDAZOLE-OH;Hydroxy Metronidazo;HYDROXY METRONIDAZOLE;Metronidazole-hydroxy;Metronidazole-OH MNZOH;Metronidazole Impurity H;2-(HydroxyMethyl)-5-nitro-;Metronidazole EP Impurity H;ROXYMETHYL-5-NITROIMIDAZOLE
CBNumber
CB6772530
Molecular Formula
C6H9N3O4
Formula Weight
187.15
MOL File
4812-40-2.mol
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Hydroxymetronidazole Property

Melting point:
118-121°C
Boiling point:
321.89°C (rough estimate)
Density 
1.4796 (rough estimate)
refractive index 
1.5800 (estimate)
storage temp. 
-20°C Freezer
solubility 
DMSO (Sparingly), Methanol (Slightly)
pka
13.28±0.10(Predicted)
form 
Solid
color 
White to Light Beige
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Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
NI5568000
HS Code 
29332900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
34007
Product name
Metronidazole-OH
Purity
VETRANAL?, analytical standard
Packaging
10MG
Price
$235
Updated
2024/03/01
Usbiological
Product number
014143
Product name
Hydroxy Metronidazole
Packaging
25mg
Price
$446
Updated
2021/12/16
TRC
Product number
H948395
Product name
HydroxyMetronidazole
Packaging
250mg
Price
$1355
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0005832
Product name
HYDROXY METRONIDAZOLE
Purity
95.00%
Packaging
250MG
Price
$1871.1
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0005832
Product name
HYDROXY METRONIDAZOLE
Purity
95.00%
Packaging
25MG
Price
$739.2
Updated
2021/12/16
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Hydroxymetronidazole Chemical Properties,Usage,Production

Description

Hydroxy metronidazole is a metabolite of metronidazole. Metronidazole belongs to the nitroimidazole class of drugs. In agricultural production, it is often used as a drug to expel parasites in animals. After being added to animal feed, metronidazole remains in eggs. Because metronidazole has a variety of toxic and side effects on the human body, especially its potential carcinogenicity and hereditary mutation effects, and metronidazole can be rapidly distributed throughout the body after entering the human body, so the residual metronidazole and its metabolites in eggs inspection is necessary.

Chemical Properties

Off-White Solid

Uses

Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle.

Definition

ChEBI: Metronidazole-OH is a member of imidazoles and a C-nitro compound.

Biological Activity

Hydroxymetronidazole is an active metabolite of the antibiotic metronidazole (Item No. 9002409). It is formed from metronidazole primarily by the cytochrome P450 (CYP) isoform CYP2A6. Hydroxymetronidazole is active against B. fragilis, B. thetaiotaomicron, B. distasonis, and B. ovatus (MICs = 1, 2, 1, and 2 μg/ml, respectively). It has been found in pork and porcine plasma.

Hydroxymetronidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Hydroxymetronidazole manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Hydroxymetronidazole 4812-40-2
Price
US $1.00-22.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100000KG
Release date
2024-07-26
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Hydroxymetronidazole 4812-40-2
Price
US $1.11/KG
Min. Order
1KG
Purity
99%
Supply Ability
10tons
Release date
2021-12-08

4812-40-2, HydroxymetronidazoleRelated Search:


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