TERT-BUTYL-4-BROMOBENZOATE

Product Name: TERT-BUTYL-4-BROMOBENZOATE
CAS No.: 59247-47-1
Chemical Name: TERT-BUTYL-4-BROMOBENZOATE
Synonyms: tert-Butyl p-BroMobenzoate;TERT-BUTYL-4-BROMOBENZOATE;Tert-butyl 4-bromobenzoate?New;4-Bromobenzoic acid tert-butyl ester;4-BroMobenzoic Acid 1,1-DiMethylethyl Ester;Benzoic acid, 4-broMo-, 1,1-diMethylethyl ester
CBNumber: CB6774796
Molecular Formula: C11H13BrO2
Formula Weight: 257.12
MOL File: 59247-47-1.mol

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TERT-BUTYL-4-BROMOBENZOATE Property

Boiling point:: 91-92 °C(Press: 1.2 Torr)
Density: 1.331±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: liquid
color: Colourless to light yellow
InChI: InChI=1S/C11H13BrO2/c1-11(2,3)14-10(13)8-4-6-9(12)7-5-8/h4-7H,1-3H3
InChIKey: BFJJYXUCGYOXDM-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)C1=CC=C(Br)C=C1

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Safety

HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: B690695
Product name: tert-Butyl4-Bromobenzoate
Packaging: 25g
Price: $1230
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0027225
Product name: TERT-BUTYL 4-BROMOBENZOATE
Purity: 95.00%
Packaging: 25G
Price: $2333.1
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB19441
Product name: tert-Butyl 4-bromobenzoate
Packaging: 25g
Price: $600
Updated: 2021/12/16

Apolloscientific

Product number: OR313102
Product name: tert-Butyl4-bromobenzoate
Packaging: 25g
Price: $675
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0027225
Product name: TERT-BUTYL 4-BROMOBENZOATE
Purity: 95.00%
Packaging: 2.5G
Price: $869
Updated: 2021/12/16

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TERT-BUTYL-4-BROMOBENZOATE Chemical Properties,Usage,Production

Uses

4-bromo substituted benzoic acid derivative, tert-Butyl-4-broMobenzoate can be used as a building block for the synthesis of various biologically active compounds.

Synthesis

865-47-4

586-75-4

59247-47-1

At -78 °C, 4-bromobenzoyl chloride (25.08 g, 114 mmol) was dissolved in THF (120 mL) and a THF solution of potassium tert-butanolate (1 M, 120 mL, 120 mmol) was slowly added. The reaction mixture was stirred at -78 °C and gradually warmed to room temperature for 2 hours. After completion of the reaction, the reaction mixture was diluted with ether. The organic phase was washed sequentially with saturated NaHCO3 solution (2×) and brine (1×) and then dried with anhydrous MgSO4. The desiccant was removed by filtration and the filtrate was concentrated under reduced pressure. The crude product was purified by fast column chromatography on silica gel, the eluent being a hexane solution of 5% ethyl acetate to give tert-butyl 4-bromobenzoate (27.96 g, 95% yield) as a colorless oil.1H NMR (600 MHz, CDCl3) δ 7.84 (d, J = 8.5 Hz, 2H), 7.54 (d, J = 8.5 Hz, 2H), 1.59 (s 9H); ESIMS calculated value 257.0 (M + + H), measured value 257.1 (M + + H).

References

[1] RSC Advances, 2016, vol. 6, # 22, p. 18165 - 18177
[2] Journal of Organic Chemistry, 2000, vol. 65, # 17, p. 5428 - 5430
[3] Patent: WO2007/2248, 2007, A2. Location in patent: Page/Page column 72-73
[4] Organic Process Research and Development, 2012, vol. 16, # 11, p. 1832 - 1845
[5] Journal of the American Chemical Society, 2016, vol. 138, # 32, p. 10293 - 10298

TERT-BUTYL-4-BROMOBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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TERT-BUTYL-4-BROMOBENZOATE Suppliers

Canada 2 China 141 India 5 United Kingdom 6 United States 15 Global 169

Anhui Yongsheng Pharmaceutical Technology Co., Ltd

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Hangzhou Copiore Chemical Co., Ltd.

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Accela ChemBio Co.,Ltd.

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Shanghai Longsheng chemical Co.,Ltd.

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Shanghai Hanhong Scientific Co.,Ltd.

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View Lastest Price from TERT-BUTYL-4-BROMOBENZOATE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: TERT-BUTYL-4-BROMOBENZOATE 59247-47-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-05-23

Henan Fengda Chemical Co., Ltd

Product: TERT-BUTYL-4-BROMOBENZOATE 59247-47-1
Price: US $8.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-23

Career Henan Chemical Co

Product: TERT-BUTYL-4-BROMOBENZOATE 59247-47-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-02

59247-47-1, TERT-BUTYL-4-BROMOBENZOATERelated Search:

4-Bromobenzoic acid TERT BUTYL 4-OXOBUTANOATE TERT-BUTYL 4-AMINO-4-CYANOPIPERIDINE-1-CARBOXYLATE tert-Butyl 4-iodopyrazole-1-carboxylate TERT-BUTYL 4-AMINO-2-FLUOROBENZOATE Tert-Butyl (1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-4-Yl)Carbamate(WX619102) (6-amino-pyridin-3-ylmethyl)-carbamic acid tert-butyl ester 4-(Boc-aMino)-3,3-diMethylpiperidine tert-butyl N-(4,4-difluoropyrrolidin-3-yl)carbamate TERT-BUTYL 3-FORMYLBENZYLCARBAMATE L-Cystine bis(t-butyl ester) dihydrochloride tert-butyl 8-oxo-3-azabicyclo[3.2.1]octane-3-carboxylate 2-(TERT-BUTOXYCARBONYL)-2,7-DIAZASPIRO[3.5]NONANE HYDROCHLORIDE tert-Butyl 3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate 1-Oxa-4,8-diazaspiro[5.5]undecan-8-carboxylic acid tert-butyl ester TERT-BUTYL 4-BROMO-3-METHYLBENZOATE TERT-BUTYL 4-BROMO-2-METHOXYBENZOATE TERT-BUTYL-2-BROMOBENZOATE

TERT-BUTYL-4-BROMOBENZOATE

4-Bromobenzoic acid tert-butyl ester

Benzoic acid, 4-broMo-, 1,1-diMethylethyl ester

4-BroMobenzoic Acid 1,1-DiMethylethyl Ester

tert-Butyl p-BroMobenzoate

Tert-butyl 4-bromobenzoate?New

59247-47-1

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Ester

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