ChemicalBook > CAS DataBase List > 2,3-DIMETHYL-4-NITROANILINE

2,3-DIMETHYL-4-NITROANILINE

Product Name
2,3-DIMETHYL-4-NITROANILINE
CAS No.
80879-86-3
Chemical Name
2,3-DIMETHYL-4-NITROANILINE
Synonyms
4-Nitro-2,3-xylidine;2,3-DIMETHYL-4-NITROANILINE;2,3-Dimethyl-4-nitrobenzenamine;2,3-Dimethyl-4-nitro-phenylamine;Benzenamine, 2,3-dimethyl-4-nitro-
CBNumber
CB6777737
Molecular Formula
C8H10N2O2
Formula Weight
166.18
MOL File
Mol file
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2,3-DIMETHYL-4-NITROANILINE Property

Melting point:
116-117℃
Boiling point:
350.4±37.0 °C(Predicted)
Density 
1.220±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
Sealed in dry,Room Temperature
pka
1.05±0.14(Predicted)
Appearance
Light yellow to yellow Solid
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Safety

HS Code 
2921420090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC
Product number
D457025
Product name
2,3-Dimethyl-4-nitroaniline
Packaging
100mg
Price
$55
Updated
2021/12/16
TRC
Product number
D457025
Product name
2,3-Dimethyl-4-nitroaniline
Packaging
500mg
Price
$170
Updated
2021/12/16
Matrix Scientific
Product number
076321
Product name
2,3-Dimethyl-4-nitroaniline
Purity
95+%
Packaging
1g
Price
$347
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0387705
Product name
2,3-DIMETHYL-4-NITROANILINE
Purity
95.00%
Packaging
5MG
Price
$497.81
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD143705
Product name
2,3-Dimethyl-4-nitroaniline
Packaging
500mg
Price
$70
Updated
2021/12/16
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2,3-DIMETHYL-4-NITROANILINE Chemical Properties,Usage,Production

Synthesis

114166-32-4

138330-47-9

59146-96-2

80879-86-3

To a solution of N-(2,3-dimethyl-6-nitrophenyl)acetamide (16.0 g, 1.0 eq.) was added a 60% aqueous sulfuric acid solution (150 mL). The reaction mixture was heated to reflux temperature and kept for 1 hour. Upon completion of the reaction, the mixture was cooled to room temperature. Subsequently, it was diluted with ice water (100 mL) and neutralized with 2N sodium hydroxide solution. The reaction mixture was extracted with ethyl acetate (3 x 50 mL). The organic layers were combined and washed sequentially with saturated sodium bicarbonate solution (2 x 50 mL) and saturated sodium chloride solution (2 x 50 mL). The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by column chromatography (eluent: 10% dichloromethane/hexane) to afford 2,3-dimethyl-6-nitroaniline (5.5 g, 43% yield) and 2,3-dimethyl-4-nitroaniline (1.5 g, 12% yield). NMR hydrogen spectral data of 2,3-dimethyl-6-nitroaniline (5.5 g, 43%): 1H NMR (CDCl3) δ 2.05 (s, 3H), 2.20 (s, 3H), 6.15 (br s, 2H), 6.45 (d, J = 8.7 Hz, 1H), 7.63 (d, J = 9.0 Hz, 1H); 1H NMR (DMSO -d6) δ 2.10 (s, 3H), 2.30 (s, 3H), 6.50 (d, J = 8.7 Hz, 1H), 7.15 (br s, 2H), 7.75 (d, J = 9.0 Hz, 1H). NMR hydrogen spectral data of 2,3-dimethyl-4-nitroaniline: 1H NMR (CDCl3) δ 2.10 (s, 3H), 2.45 (s, 3H), 4.05 (br s, 2H), 6.45 (d, J = 9.0 Hz, 1H), 7.65 (d, J = 8.7 Hz, 1H); 1H NMR (DMSO-d6) δ 2.00 ( s, 3H), 2.35 (s, 3H), 6.12 (br s, 2H), 6.53 (d, J = 9.0 Hz, 1H), 7.63 (d, J = 9.0 Hz, 1H).

References

[1] Patent: US6353006, 2002, B1. Location in patent: Page column 28-29

2,3-DIMETHYL-4-NITROANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-DIMETHYL-4-NITROANILINE Suppliers

China 51 France 1 India 1 The Netherlands 1 United Kingdom 2 United States 4 Global 60
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
021-31038972,31038973 17321035817
Fax
+86-21-51385350
Email
sales@harvest-chem.com
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China
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
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64
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
13761987713
Fax
021 51613951
Email
hxzheng@sunwaypharm.cn
Country
China
ProdList
8667
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Bide Pharmatech Ltd.
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400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
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China
ProdList
40000
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Xinyanhe Pharmatech Co.,Ltd
Tel
0519-85252752 15366845260
Fax
86-0519-85683352
Email
taihuaren@vip.163.com
Country
China
ProdList
1067
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Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
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5734
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Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
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9793
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50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 17714375163
Email
yftan@aikonchem.com
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China
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16676
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50
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
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JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
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12000
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80879-86-3, 2,3-DIMETHYL-4-NITROANILINERelated Search:


  • 2,3-DIMETHYL-4-NITROANILINE
  • 2,3-Dimethyl-4-nitrobenzenamine
  • 4-Nitro-2,3-xylidine
  • 2,3-Dimethyl-4-nitro-phenylamine
  • Benzenamine, 2,3-dimethyl-4-nitro-
  • 80879-86-3