METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATE

Product Name: METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATE
CAS No.: 914347-01-6
Chemical Name: METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATE
Synonyms: Methyl 1-(5-bromopyrimidin-2-yl);METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATE;4-Piperidinecarboxylic acid, 1-(5-bromo-2-pyrimidinyl)-, methyl ester
CBNumber: CB6780009
Molecular Formula: C11H14BrN3O2
Formula Weight: 300.15
MOL File: 914347-01-6.mol

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METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATE Property

storage temp.: Sealed in dry,Room Temperature
Appearance: White to light yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M293823
Product name: Methyl1-(5-Bromopyrimidin-2-yl)piperidine-4-carboxylate
Packaging: 500mg
Price: $155
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: COR0004277
Product name: METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATE
Purity: 95.00%
Packaging: 1G
Price: $253.05
Updated: 2021/12/16

Matrix Scientific

Product number: 071967
Product name: Methyl 1-(5-bromopyrimidin-2-yl)piperidine-4-carboxylate
Purity: 95+%
Packaging: 5g
Price: $500
Updated: 2021/12/16

Matrix Scientific

Product number: 071967
Product name: Methyl 1-(5-bromopyrimidin-2-yl)piperidine-4-carboxylate
Purity: 95+%
Packaging: 1g
Price: $185
Updated: 2021/12/16

Matrix Scientific

Product number: 071967
Product name: Methyl 1-(5-bromopyrimidin-2-yl)piperidine-4-carboxylate
Purity: 95+%
Packaging: 10g
Price: $714
Updated: 2021/12/16

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METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATE Chemical Properties,Usage,Production

Synthesis

2971-79-1

32779-36-5

914347-01-6

Step 1: DIPEA (4 mL, 23.20 mmol) was added dropwise to a solution of acetonitrile (80 mL) containing 5-bromo-2-chloropyrimidine (3.0 g, 15.50 mmol) under nitrogen protection. Subsequently, methyl 4-piperidinecarboxylate (3.321 g, 23.20 mmol) was added to the reaction system. The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the solvent was concentrated to dryness by rotary evaporator. Deionized water and ethyl acetate (EtOAc) were added to quench the reaction and the organic layer was separated. The organic phase was dried over anhydrous sodium sulfate and concentrated again to dryness. The crude product was purified by silica gel column chromatography with an elution gradient of heptane/ethyl acetate (100:0 to 0:100). The fractions containing the target product were collected, combined and concentrated to dryness to give methyl 1-(5-bromopyrimidin-2-yl)piperidine-4-carboxylate (1.84 g, 41% yield) as a white solid.

References

[1] Patent: WO2018/138356, 2018, A1. Location in patent: Page/Page column 35; 40-41

METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATE Suppliers

China 23 India 1 United Kingdom 1 United States 8 Global 33

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
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Email: sales@chemreagents.com
Country: United States
ProdList: 10186
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
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Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
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Amadis Chemical Company Limited

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Biokitchen

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Aikon International Limited

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Yujinpharma(Tianjin) Technology Co.,Ltd.

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Country: China
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Shanghai Jizhi Biochemical Technology Co. Ltd.

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Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
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Country: China
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HONEST PHARM CO.,LTD.

Tel: 0531-59840128 19353175568
Fax: QQ:3379530787
Email: zpy8217@163.com
Country: China
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View Lastest Price from METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATE manufacturers

Career Henan Chemica Co

Product: METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATE 914347-01-6
Price: US $0.01/KG
Min. Order: 1KG
Purity: 95%-99%
Supply Ability: 1kg; 5kg; 10kg
Release date: 2020-10-28

914347-01-6, METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATERelated Search:

METHYL 1-(5-BROMOPYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLATE

Methyl 1-(5-bromopyrimidin-2-yl)

4-Piperidinecarboxylic acid, 1-(5-bromo-2-pyrimidinyl)-, methyl ester

914347-01-6