ChemicalBook > CAS DataBase List > 1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER

1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER

Product Name
1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
CAS No.
28246-87-9
Chemical Name
1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
Synonyms
Ethyl 1-cyanocyclobutane-1-carboxylate;ethyl 1-cyanocyclobutanecarboxylate;1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER;1-Cyano-Cyclobutanecarboxylic Acid Ethyl Este;Cyclobutanecarboxylic acid, 1-cyano-, ethyl ester;*Guaiacol Impurity 1 (Guaiacol EP Impurity A)(Pyrocatechol);(Z)-3-hydroxy-1-[5-(thiophen-2-ylmethyl)-2-furanyl]-3-(1H-1,2,4-triazol-5-yl)-2-propen-1-one
CBNumber
CB6801258
Molecular Formula
C8H11NO2
Formula Weight
153.18
MOL File
28246-87-9.mol
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1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER Property

Boiling point:
215.5-216 °C(Press: 762 Torr)
Density 
1.09±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
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Safety

HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

TRC
Product number
E926323
Product name
Ethyl1-cyanocyclobutane-1-carboxylate
Packaging
250mg
Price
$75
Updated
2021/12/16
TRC
Product number
E926323
Product name
Ethyl1-cyanocyclobutane-1-carboxylate
Packaging
25mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0006613
Product name
1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
Purity
95.00%
Packaging
250MG
Price
$1460.15
Updated
2021/12/16
AK Scientific
Product number
2753AB
Product name
Ethyl1-cyanocyclobutanecarboxylate
Packaging
10g
Price
$420
Updated
2021/12/16
Matrix Scientific
Product number
083631
Product name
Ethyl 1-cyanocyclobutanecarboxylate
Purity
97%
Packaging
1g
Price
$561
Updated
2021/12/16
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1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Uses

1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical and pharmaceutical production process.

Synthesis


4-(9>-cyclopentyl-5'-methyl-6>-oxo-5>,6>,8>,9>- tetrahydrospiro[cyclobutane-l,7'-pyrimido[4,5-b][l,4]diazepine]-2'-ylamino)-3- methoxybenzoic acid; [0521] Ethyl 1-cyanocyclobutanecarboxylate; To a solution of sodium ethoxide (21wt% in EtOH, 5.79 rnL, 15.5 mmol) in EtOH (25 mL), was added ethyl cyanoacetate(1.12 mL, 10.5 mmol), followed shortly thereafter by 1,1-dibromopropane (1.12 mL, 10 mmol). The reaction mixture was refluxed for 3 hrs. It was then concentrated, and diluted to ethyl acetate. The organic layer was washed with NaHCCh, brine, water, dried over Na2SO4 and concentrated in vacuo to obtain ethyl 1-cyanocyclobutanecarboxylate (1.17 g, 74% yield) as a red liquid. It was used directly for next step reaction.

1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER Suppliers

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View Lastest Price from 1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER manufacturers

Career Henan Chemical Co
Product
1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER 28246-87-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98%-99.9%
Supply Ability
100kg
Release date
2020-01-10

28246-87-9, 1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTERRelated Search:

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile methyl 1-cyanocyclobutanecarboxylate 1-cyanocyclobutanecarboxylic acid Ethyl cyclobutanecarboxylate 1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER

  • 1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
  • ethyl 1-cyanocyclobutanecarboxylate
  • Ethyl 1-cyanocyclobutane-1-carboxylate
  • (Z)-3-hydroxy-1-[5-(thiophen-2-ylmethyl)-2-furanyl]-3-(1H-1,2,4-triazol-5-yl)-2-propen-1-one
  • Cyclobutanecarboxylic acid, 1-cyano-, ethyl ester
  • 1-Cyano-Cyclobutanecarboxylic Acid Ethyl Este
  • *Guaiacol Impurity 1 (Guaiacol EP Impurity A)(Pyrocatechol)
  • 28246-87-9