ChemicalBook > CAS DataBase List > Alkyne tyramide
Alkyne tyramide
- Product Name
- Alkyne tyramide
- CAS No.
- 1694495-59-4
- Chemical Name
- Alkyne tyramide
- Synonyms
- Alkyne-phenol;Alkyne tyramide;Alkyne tyramide, 10 mM in DMSO;N-(4-Hydroxyphenethyl)pent-4-ynamide;4-Pentynamide, N-[2-(4-hydroxyphenyl)ethyl]-;Alkyne tyramide,membrane,mitochondria,topology,Inhibitor,inhibit,APEX2,substrate,yeast
- CBNumber
- CB68065964
- Molecular Formula
- C13H15NO2
- Formula Weight
- 217.26
- MOL File
- 1694495-59-4.mol
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Alkyne tyramide Property
- Boiling point:
- 464.5±35.0 °C(Predicted)
- Density
- 1.126±0.06 g/cm3(Predicted)
- pka
- 10.01±0.15(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
TCI Chemical
- Product number
- H1847
- Product name
- Alkyne Tyramide
- Packaging
- 50MG
- Price
- $132
- Updated
- 2025/07/31
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Alkyne tyramide Chemical Properties,Usage,Production
Uses
Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins[1]. Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
References
[1] Li Y, et al. A Clickable APEX Probe for Proximity-Dependent Proteomic Profiling in Yeast. Cell Chem Biol. 2020;27(7):858-865.e8. DOI:10.1016/j.chembiol.2020.05.006
Alkyne tyramide Preparation Products And Raw materials
Raw materials
Preparation Products
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