4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide

Product Name: 4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide
CAS No.: 1187188-59-5
Chemical Name: 4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide
Synonyms: Crisaborole Impurity 23;Crisaborole Impurity 53;Crisaborole Impurity 11;Benzamide, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-;4-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)benzamide;4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzamide
CBNumber: CB68087742
Molecular Formula: C14H12BNO4
Formula Weight: 269.06
MOL File: 1187188-59-5.mol

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4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide Property

Melting point:: >188°C (dec.)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
color: Pale Red to Red
Stability:: Hygroscopic
InChI: InChI=1S/C14H12BNO4/c16-14(17)9-1-3-11(4-2-9)20-12-5-6-13-10(7-12)8-19-15(13)18/h1-7,18H,8H2,(H2,16,17)
InChIKey: BNNSMPLZLMPJQX-UHFFFAOYSA-N
SMILES: C(N)(=O)C1=CC=C(OC2=CC=C3B(O)OCC3=C2)C=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide Chemical Properties,Usage,Production

Uses

4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide is used in the preparation of substituted benzoxaborole and related boron-containing small molecules as anti-inflammatory agents.

General Description

4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide, also known as Crisaborole Impurity 11, is an impurity of Crisaborole. Crisaborole topical is used to treat mild to moderate atopic dermatitis (eczema).

4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide Suppliers

China 47 India 2 Global 49

Adamas Reagent, Ltd.

Tel: 400-6009262 15618770481
Fax: 021-64823266
Email: yhx@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7440
Advantage: 65

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
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Email: 3001272453@qq.com
Country: China
ProdList: 5157
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Quality Control Solutions Ltd.

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Country: China
ProdList: 18422
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Hubei Yangxin Medical Technology Co., Ltd.

Tel: 15374522761
Fax: QQ:2853117752
Email: 3003392093@yongstandards.com
Country: China
ProdList: 9999
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Shenzhen Botel Biotechnology Co. Ltd.

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TOSUN PHARM

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ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
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Yangzhou Changhua Biotechnology Co., Ltd.

Tel: 15189846850 13815846020
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Shanghai Star Pharmaceutical Chemical Technology Co., Ltd.

Tel: 021-58521787 17701827760
Email: starpharmsh@gmail.com
Country: China
ProdList: 301
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View Lastest Price from 4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide manufacturers

Moxin Chemicals

Product: Crisaborole Impurity 8 1187188-59-5
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 95%+
Supply Ability: 10000
Release date: 2025-01-21

Guangzhou Tosun Pharmaceutical Limited

Product: Crisaborole Impurity 11 1187188-59-5
Price: US $0.00/mg
Min. Order: 1mg
Purity: above 96%
Supply Ability: 50mg
Release date: 2023-05-29

1187188-59-5, 4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamideRelated Search:

Benzamide, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-

4-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)benzamide

Crisaborole Impurity 11

4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzamide

Crisaborole Impurity 53

Crisaborole Impurity 23

1187188-59-5

C14H12BNO4