(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

ChemicalBook > CAS DataBase List > (1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

Product Name: (1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione
CAS No.: 2300966-23-6
Chemical Name: (1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione
Synonyms: (1R)-7-Chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione;7-chloro-6-fluoro-(1M)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione;(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione;Pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione, 7-chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-, (1R)-
CBNumber: CB68206451
Molecular Formula: C16H14ClFN4O2
Formula Weight: 348.76
MOL File: 2300966-23-6.mol

Less

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Property

Density: 1.397±0.06 g/cm3(Predicted)
pka: 6.91±0.20(Predicted)
InChI: InChI=1S/C16H14ClFN4O2/c1-7(2)11-12(8(3)4-5-19-11)22-14-9(15(23)21-16(22)24)6-10(18)13(17)20-14/h4-7H,1-3H3,(H,21,23,24)
InChIKey: OXJTVPMAMRSGNT-UHFFFAOYSA-N
SMILES: O=C1NC(=O)C2=CC(F)=C(Cl)N=C2N1C1C(=CC=NC=1C(C)C)C

Less

Hazard and Precautionary Statements (GHS)

Less

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Chemical Properties,Usage,Production

Definition

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione is an intermediate of Sotorasib which is used to treat a particular type of lung cancer.

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Preparation Products And Raw materials

Raw materials

Preparation Products

Less

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Suppliers

China 42 Global 42

Heading （Nanjing）Pharmtechnologies Co., Ltd.

Tel: 025-58467899-832 13382406280
Fax: 025-58467899
Email: liucheng@headingpharm.com
Country: China
ProdList: 45
Advantage: 58

Shanghai Hope Chem Co., Ltd.，

Tel: +21-18501659228 18501659228
Fax: sales@hope-chem.com
Email: info@hope-chem.com
Country: China
ProdList: 481
Advantage: 55

Suzhou Ryan Pharmaceutical Technology Co., Ltd.

Tel: 0512-68780025 18962125825
Email: sales@ryanchem.com
Country: China
ProdList: 163
Advantage: 62

Suli Pharmaceutical Technology Co., Ltd.

Tel: 021-58086325-8060 13636568474
Fax: 021-51972827
Email: yingjie.zhang@suli.com
Country: China
ProdList: 108
Advantage: 58

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

BEIJING EAGLE SKY PHARMATECH CO., LTD

Tel: 010-88755821 13911359480
Email: sophia_818@126.com
Country: China
ProdList: 328
Advantage: 55

Cangzhou Enke Pharma-tech Co., Ltd.

Tel: 0317-5296180 15533709196
Fax: 0317-5106596
Email: sale@enkepharma.com
Country: China
ProdList: 1898
Advantage: 55

ChengDu TongChuangYuan Pharmaceutical Co.Ltd

Tel: 028-83379370 13880556291
Fax: 028-87747383
Email: tcy@tcypharm.com
Country: China
ProdList: 6268
Advantage: 58

Shanghai SuperLan Chemcial Technique Centre

Tel: 021-2022843681 15618226720
Fax: +86-21-51601218
Email: lucy@atkchemical.com
Country: China
ProdList: 9204
Advantage: 58

Aikon International Limited

Tel: 025-58851090 13611564524
Fax: (6)02557626880
Email: lwan@aikonchem.com
Country: China
ProdList: 15951
Advantage: 58

Jinan Kabotang Biological Technology Co.,Ltd.

Tel: 0531-61320525 15866703830
Email: 495745175@qq.com
Country: China
ProdList: 7990
Advantage: 58

Jinan Carbotang Biotech Co.,Ltd.

Tel: +8615866703830
Email: figo.gao@foxmail.com
Country: China
ProdList: 8497
Advantage: 58

Shanghai Yanze Chemical Co., Ltd.

Tel: 021-13773155751 19975051755
Email: 260924549@qq.com
Country: China
ProdList: 8904
Advantage: 58

Wuhan Dingxintong Pharmaceutical Co. , Ltd.

Tel: 027-027-52344656 15871722230
Fax: 2796190295
Email: 15871722230@163.com
Country: China
ProdList: 4855
Advantage: 58

Chunchuang (Wuhan) Technology Co., Ltd

Tel: 15342225168
Email: yutianchun2007@126.com
Country: China
ProdList: 10002
Advantage: 58

Shanghai Dexuan Pharmaceutical Technology Co., Ltd

Tel: 1701086315
Fax: 1701086315@qq.com
Email: dexuanpharma@126.com
Country: China
ProdList: 9475
Advantage: 58

Jiangxi ravel Biotechnology Co.,Ltd

Tel: 400-880-2824; 13184580281
Fax: 400-880-2824
Email: hj@ruiweier.cn
Country: China
ProdList: 2737
Advantage: 58

Nanjing webright Pharmaceutical Technology Co., Ltd

Tel: 18066048793; 18014498793
Email: 1504914633@qq.com
Country: China
ProdList: 829
Advantage: 58

Jiangxi ravel Biotechnology Co.,Ltd

Tel: 185-0276-2003 18502762003;
Email: 435918333@qq.com
Country: China
ProdList: 2306
Advantage: 58

Nanajing Chenruisheng Biomedical Technology Ltd

Tel: 18805148037
Email: 1277392432@qq.com
Country: China
ProdList: 151
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55013243 15324716602
Email: 2853979810@qq.com
Country: China
ProdList: 10018
Advantage: 58

Cangzhou Kangrui Medical Technology Co., LTD

Tel: 18632776803
Email: 355803330@qq.com
Country: China
ProdList: 554
Advantage: 58

Aobolihui

Tel: 0917-18691729 18691729963
Email: 2553382659@qq.com
Country: China
ProdList: 4747
Advantage: 58

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054 13417589054
Email: trendseenbio@gmail.com
Country: China
ProdList: 9470
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-400-8210725
Email: malulu@leyan.com
Country: China
ProdList: 39990
Advantage: 58

Wuhan Jingkangen Biomedical Technology Co., Ltd

Tel: 13720134139 13720134139
Email: orders@jknbiochem.com
Country: China
ProdList: 5797
Advantage: 58

Nanjing Joyin Pharmachem Co.,Ltd

Tel: 025-84670162-813 18761603731
Email: lhm@joyin.cc
Country: China
ProdList: 100
Advantage: 58

Nanjing Lebang Pharmaceutical Technology Co., Ltd

Tel: 18860950986
Email: tangmanman@lebangpharma.com
Country: China
ProdList: 538
Advantage: 58

HANGZHOU KELAI BIOMEDICAL TECHNOLOGY Co., Ltd.

Tel: 18957050573
Email: 752803249@qq.com
Country: China
ProdList: 245
Advantage: 58

shanghai yayu biomedical co.,ltd

Tel: 021-54370211 18051886391
Email: 3007215920@qq.com
Country: China
ProdList: 2989
Advantage: 58

Jiangxi Puxin Biotechnology Co., Ltd

Tel: 15867635987 15867635987
Email: jasonhu09@163.com
Country: China
ProdList: 285
Advantage: 58

Baoji Didu Pharmaceutical and Chemical Co., Ltd

Tel: 02961856358 15829046862
Email: 1035@dideu.com
Country: China
ProdList: 10010
Advantage: 58

Shanghai Langruibang Pharmaceutical Technology Co., Ltd

Tel: 010-88755821 18612220856
Email: marketing@langrb.com
Country: China
ProdList: 213
Advantage: 58

Pushan Industry (Shaanxi) Co., Ltd

Tel: 029-81310890 18165209495
Email: 2929288192@qq.com
Country: China
ProdList: 9947
Advantage: 58

Olix (Shanghai) Pharmaceutical Technology Co., Ltd

Tel: 17316404525
Email: 209533805@qq.com
Country: China
ProdList: 9762
Advantage: 58

Shanghai Shenju Chemical Co., LTD

Tel: 13167128868
Email: 173446357@qq.com
Country: China
ProdList: 4938
Advantage: 58

Anqing Duohui Biotechnology Co., Ltd.

Tel: 18521071293
Email: eric_zhao1986@hotmail.com
Country: China
ProdList: 174
Advantage: 58

Cangzhou Kangrui Pharma Tech Co. Ltd.,

Tel: +86-18632776803 +86-13833998158
Email: cangzhoukangrui@126.com
Country: China
ProdList: 737
Advantage: 58

Wuhan Jingkang en Biomedical Technology Co., Ltd

Tel: +8613720134139
Email: orders@jknbiochem.com
Country: China
ProdList: 5221
Advantage: 58

Jiangsu Guotai Guomian Trading Co. Ltd.

Tel: +86-512-58916079 +86-13601562190
Email: pharmachem@gtgmt.com
Country: China
ProdList: 148
Advantage: 58

Hangzhou Qiwei Pharmatech Co.,Ltd

Tel: 13282840061
Email: mw@qwpharmatech.com
Country: China
ProdList: 109
Advantage: 58

Heading （Nanjing）Pharmtechnologies Co., Ltd.

Tel: +86-25-58467899-832 +86-13382406280
Email: liucheng@headingpharm.com
Country: China
ProdList: 46
Advantage: 58

2300966-23-6, (1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dioneRelated Search:

Pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione, 7-chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-, (1R)-

7-chloro-6-fluoro-(1M)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

(1R)-7-Chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

2300966-23-6

C16H14ClFN4O2