6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline

Product Name: 6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline
CAS No.: 1936429-80-9
Chemical Name: 6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline
Synonyms: 6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline;Quinoline, 6-bromo-7-(difluoromethyl)-1,2,3,4-tetrahydro-
CBNumber: CB68224822
Molecular Formula: C10H10BrF2N
Formula Weight: 262.09
MOL File: 1936429-80-9.mol

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6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline Property

Boiling point:: 328.6±42.0 °C(Predicted)
Density: 1.485±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
pka: 3.60±0.20(Predicted)
Appearance: White to yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline Chemical Properties,Usage,Production

Uses

6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.

6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline Suppliers

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1936429-80-9, 6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinolineRelated Search:

7-METHYL-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE 6-Bromo-7-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline Quinoline, 1,2,3,4-tetrahydro-6-(methylthio)- 7-Quinolinecarboxylic acid, 6-bromo-1,2,3,4-tetrahydro- 7-Methyl-1,2,3,4-tetrahydroquinoline 1,2,3,4-tetrahydroquinoline-2-carboxamide 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline

Quinoline, 6-bromo-7-(difluoromethyl)-1,2,3,4-tetrahydro-

6-Bromo-7-(difluoromethyl)-1,2,3,4-tetrahydroquinoline

1936429-80-9