ChemicalBook > CAS DataBase List > ALC-0159

ALC-0159

Physical Form Uses

Product Name: ALC-0159
CAS No.: 1849616-42-7
Chemical Name: ALC-0159
Synonyms: mPEG-DTA;mPEG48-TDA;MPEG2000-DTA;Lipid ALC-0159;ALC-0159 ，E0446;ALC-0159(mPEG-DTA);Mpeg-N,N-Ditetradecylacetamide;2-(2-methoxyethoxy)-N,N-ditetradecylacetamide;Methoxypolyethyleneglycolbis(tetradecylacetamide);Methoxypoly(ethylene glycol) ditetradecylacetamide
CBNumber: CB68366296
Molecular Formula: (C2H4O)nC31H63NO2
Formula Weight: 0
MOL File: 1849616-42-7.mol

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ALC-0159 Property

solubility: DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml; DMSO: Slightly Soluble; Ethanol: 1 mg/ml
form: A solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals

Product number: 028219
Product name: ALC-0159
Packaging: 002
Price: $1100
Updated: 2021/12/16

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ALC-0159 Chemical Properties,Usage,Production

Physical Form

White to Yellow Solid

Uses

Methoxypoly(ethylene glycol) ditetradecylacetamide can be used in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Description

ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). It is a non-ionic surfactant by its nature. It has been deployed in the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine that contains the active ingredient tozinameran.

Uses

ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient[1].

Application

References

[1] S Moein Moghimi, et al. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021 Mar 3;29(3):898-900. DOI:10.1016/j.ymthe.2021.01.030

ALC-0159 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ALC-0159 manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: Methoxypoly(ethylene glycol) ditetradecylacetamide 1849616-42-7
Price: US $0.00-0.00/G
Min. Order: 1G
Purity: 98%
Supply Ability: 1
Release date: 2021-06-01

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: Methoxypoly(ethylene glycol) ditetradecylacetamide 1849616-42-7
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 98%
Supply Ability: 1
Release date: 2021-06-22

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: ALC-0159（mPEG-DTA） 1849616-42-7
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle , 10g/bottle, 100g/bottle
Release date: 2024-11-25

1849616-42-7, ALC-0159Related Search:

Methoxypoly(ethylene glycol) ditetradecylacetamide

2-[(polyethylene glycol)-2000]-N,N ditetradecylacetamide(ALC- 0159)

Poly(oxy-1,2-ethanediyl), α-[2-(ditetradecylamino)-2-oxoethyl]-ω-methoxy-

2-(2-methoxyethoxy)-N,N-ditetradecylacetamide, ammonia salt

Lipid ALC-0159

mPEG-DTA

α-[2-(Ditetradecylamino)-2-oxoethyl]-ω-methoxy-Poly(oxy-1,2-ethanediyl)

ALC0159,conjugate,lipid,vaccine,ALC 0159,ALC-0159,inhibit,excipient,Inhibitor

MPEG2000-DTA

Methoxypolyethyleneglycoloxy(2000)-N,N-ditetradecylacetamide

ALC-0159(mPEG-DTA)

2-[(Polyethylene glycol)]-N,N-ditetradecylacetamide PEG2000

2-(2-methoxyethoxy)-N,N-ditetradecylacetamide

mPEG48-TDA

N,N-ditetradecyl-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98,101,104,107,110,113,116,119,122,125,128,131,134,137-hexatetracontaoxanonatriacontahectan-139-amide

Methoxypolyethyleneglycolbis(tetradecylacetamide)

Mpeg-N,N-Ditetradecylacetamide

2-[(Polyethylene glycol)]-N,N-ditetradecylacetamide PEG10000

2-[(Polyethylene glycol)]-N,N-ditetradecylacetamide PEG30000

2-[(Polyethylene glycol)]-N,N-ditetradecylacetamide PEG40000

ALC-0159 ，E0446

1849616-42-7

C2H4OnC31H63NO2

peg