ChemicalBook > CAS DataBase List > L-759,633

L-759,633

Product Name
L-759,633
CAS No.
174627-50-0
Chemical Name
L-759,633
Synonyms
L-759;L 759;L-759,633;L759633,L-759633;(6aR,10aR)-1-methoxy-6,6,9-trimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene;(6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran;6H-Dibenzo[b,d]pyran, 3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-, (6aR,10aR)-
CBNumber
CB6837204
Molecular Formula
C26H40O2
Formula Weight
384.59
MOL File
174627-50-0.mol
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L-759,633 Property

Boiling point:
447.9±45.0 °C(Predicted)
Density 
0.956±0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
Ethanol:20.0(Max Conc. mg/mL);52.0(Max Conc. mM)
PBS (pH 7.2):0.25(Max Conc. mg/mL);0.65(Max Conc. mM)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10009280
Product name
L-759,633
Purity
>98%
Packaging
1mg
Price
$31
Updated
2024/03/01
Cayman Chemical
Product number
10009280
Product name
L-759,633
Purity
>98%
Packaging
5mg
Price
$133
Updated
2024/03/01
Cayman Chemical
Product number
10009280
Product name
L-759,633
Purity
>98%
Packaging
10mg
Price
$234
Updated
2024/03/01
Cayman Chemical
Product number
10009280
Product name
L-759,633
Purity
>98%
Packaging
25mg
Price
$510
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0006768
Product name
L-759633
Purity
95.00%
Packaging
1MG
Price
$568.79
Updated
2021/12/16
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L-759,633 Chemical Properties,Usage,Production

Description

L-759,633 is a high-affinity peripheral cannabinoid receptor (CB2)-selective agonist with Ki values of 6.4 and 1,043 nM for CB2 and central cannabinoid (CB1) receptors, respectively. L-759,633 inhibits forskolin-stimulated cyclic AMP production in CHO cells transfected with CB2 or CB1 receptors with IC50 values of 8.1 nM and 10 μM, respectively.

Uses

L 759633 is a cannabinoid receptor (CB2) selective agonist and a structural analogues of ??9-Tetrahydro Cannabinol, an active constituent of cannabis. L 759633 has analgesic and anti-inflammatory properties.

Definition

ChEBI: 6h-dibenzo[b,d]pyran, 3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-, (6ar,10ar)- is a 1-benzopyran.

Biological Activity

High affinity, selective CB 2 receptor agonist (K i values are 6.4 and 1043 nM for CB 2 and CB 1 receptors respectively). Potently inhibits forskolin-stimulated cAMP production via CB 2 receptors expressed in CHO cells (EC 50 = 8.1 nM).

L-759,633 Preparation Products And Raw materials

Raw materials

Preparation Products

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L-759,633 Suppliers

CHINA 17 Germany 1 Japan 1 Switzerland 1 United Kingdom 1 United States 6 Global 27
3B Pharmachem (Wuhan) International Co.,Ltd.
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sales@chemegen.com
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174627-50-0, L-759,633Related Search:

DELTA-8-THC L-759,633 5-(1,1-DIMETHYL-HEPTYL)RESORCINOL 4-(2-ETHOXYPHENYL)-2-METHYL-1-BUTENE 1-(1 1-DIMETHYLHEPTYL)-3 5-DIMETHOXYBEN& ethyl-delta-8-tetrahydrocannabinol (6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN

  • L-759,633
  • (6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran
  • (6aR,10aR)-1-methoxy-6,6,9-trimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene
  • 6H-Dibenzo[b,d]pyran, 3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-, (6aR,10aR)-
  • L 759
  • L-759
  • L759633,L-759633
  • 174627-50-0
  • C26H40O2
  • Cannabinoid receptor