ChemicalBook > CAS DataBase List > 3-(4-HYDROXYMETHYL-PHENYL)-PROPIONIC ACID ETHYL ESTER

3-(4-HYDROXYMETHYL-PHENYL)-PROPIONIC ACID ETHYL ESTER

Product Name
3-(4-HYDROXYMETHYL-PHENYL)-PROPIONIC ACID ETHYL ESTER
CAS No.
107859-98-3
Chemical Name
3-(4-HYDROXYMETHYL-PHENYL)-PROPIONIC ACID ETHYL ESTER
Synonyms
Ethyl 3-(4-(hydroxymethyl);Ethyl 3-[4-(Hydroxymethyl)phenyl]propionate;Ethyl 3-[4-(hydroxymethyl)phenyl]propanoate;Benzenepropanoic acid,4-(hydroxymethyl)-, ethyl ester;3-(4-HYDROXYMETHYL-PHENYL)-PROPIONIC ACID ETHYL ESTER
CBNumber
CB6839400
Molecular Formula
C12H16O3
Formula Weight
208.25
MOL File
107859-98-3.mol
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3-(4-HYDROXYMETHYL-PHENYL)-PROPIONIC ACID ETHYL ESTER Property

Boiling point:
155-163 °C(Press: 0.5 Torr)
Density 
1.101±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
14.43±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0372318
Product name
3-(4-HYDROXYMETHYL-PHENYL)-PROPIONIC ACID ETHYL ESTER
Purity
95.00%
Packaging
5MG
Price
$501.5
Updated
2021/12/16
Crysdot
Product number
CD12182045
Product name
Ethyl3-(4-(hydroxymethyl)phenyl)propanoate
Purity
95+%
Packaging
5g
Price
$743
Updated
2021/12/16
Ambeed
Product number
A222082
Product name
Ethyl3-(4-(hydroxymethyl)phenyl)propanoate
Purity
95%
Packaging
5g
Price
$781
Updated
2021/12/16
Crysdot
Product number
CD12182045
Product name
Ethyl3-(4-(hydroxymethyl)phenyl)propanoate
Purity
95+%
Packaging
10g
Price
$1238
Updated
2021/12/16
Ambeed
Product number
A222082
Product name
Ethyl3-(4-(hydroxymethyl)phenyl)propanoate
Purity
95%
Packaging
100mg
Price
$63
Updated
2021/12/16
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3-(4-HYDROXYMETHYL-PHENYL)-PROPIONIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Synthesis

51828-89-8

107859-98-3

(B) A mixture of ethyl (E)-3-(4-formylphenyl)acrylate (2 g, 9.79 mmol), Pd/C (1 g, 10 wt%), and ethanol (50 mL) was placed in an autoclave reactor and hydrogenated for 2 h at 3.5 atm hydrogen pressure. Upon completion of the reaction, the catalyst was removed by filtration. The filtrate was concentrated under reduced pressure and the resulting residue was purified by silica gel column chromatography (eluent: 0-15% ethyl acetate/petroleum ether) to afford ethyl 3-(4-(hydroxymethyl)phenyl)propionate (1.54 g, 76% yield) as a colorless liquid.LC/MS analysis: calculated value (C12H16O3) 208.25, measured value 191.0 [M-OH] +.

References

[1] Patent: WO2016/57731, 2016, A1. Location in patent: Page/Page column 173
[2] Patent: US2017/290800, 2017, A1. Location in patent: Paragraph 0728
[3] Patent: EP1785421, 2007, A1. Location in patent: Page/Page column 36

3-(4-HYDROXYMETHYL-PHENYL)-PROPIONIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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