2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
- Product Name
- 2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
- CAS No.
- 41179-33-3
- Chemical Name
- 2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
- Synonyms
- CMPD-1;CMD1;SRA1;MK2a Inhibitor;CMPD-1 (CMPD 1;Steroid receptor RNA activator 1;ANTI-SOX9 antibody produced in mouse;MK2a Inhibitor - CAS 41179-33-3 - Calbiochem;ANTI-SRA1 (C-TERM) antibody produced in rabbit;Monoclonal Anti-SOX9 antibody produced in mouse
- CBNumber
- CB6840374
- Molecular Formula
- C22H20FNO2
- Formula Weight
- 349.4
- MOL File
- 41179-33-3.mol
2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE Property
- Melting point:
- 128-130 °C
- Boiling point:
- 585.0±50.0 °C(Predicted)
- Density
- 1.229±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble to 100 mM in DMSO and to 100 mM in ethanol
- form
- Pale yellow solid
- pka
- 10.11±0.26(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- AMAB90795
- Product name
- Monoclonal Anti-SOX9 antibody produced in mouse
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, clone CL0639, purified immunoglobulin, buffered aqueous glycerol solution
- Packaging
- 25μL
- Price
- $294
- Updated
- 2024/03/01
- Product number
- WH0006662M2
- Product name
- Monoclonal Anti-SOX9 antibody produced in mouse
- Purity
- clone 3C10, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100μG
- Price
- $524
- Updated
- 2024/03/01
- Product number
- AMAB90795
- Product name
- Monoclonal Anti-SOX9 antibody produced in mouse
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, clone CL0639, purified immunoglobulin, buffered aqueous glycerol solution
- Packaging
- 100μL
- Price
- $514
- Updated
- 2024/03/01
- Product number
- 475863
- Product name
- MK2a Inhibitor - CAS 41179-33-3 - Calbiochem
- Packaging
- 5mg
- Price
- $318
- Updated
- 2024/03/01
- Product number
- 17325
- Product name
- MK2a Inhibitor
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE Chemical Properties,Usage,Production
Uses
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
Uses
Monoclonal Anti-SOX9 antibody produced in mouse has been used in immunofluorescence.
Definition
ChEBI: 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide is a member of biphenyls.
General Description
Sex determining region Y box 9 (Sox9) is a transcription protein, that belongs to the high-mobility-group box class DNA-binding proteins. It is located on human chromosome 17q24.
Biological Activity
Non-ATP-competitive, selective inhibitor of p38 α -mediated MK2a (mitogen-activated protein kinase-activated protein kinase 2a) phosphorylation (apparent K i = 330 nM). Does not inhibit p38 α -mediated phosphorylation of the two other known p38 substrates, MBP and ATF-2.
Biochem/physiol Actions
Sex determining region Y box 9 (Sox9) participates in the human development processes. It helps to maintain the pluripotent cells at the time of pancreatic organogenesis. In adult tissues, Sox9 modulates stem and progenitor cells. Haploinsufficiency of Sox9 results in campomelic dysplasia (CD), a disease characterized by bowed femurs and tibiae, hypoplastic scapulae, 11 pairs of ribs, pelvic malformations, Robin sequence and clubbed feet.
storage
Store at RT
2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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