Alcuronium Chloride
- Product Name
- Alcuronium Chloride
- CAS No.
- 15180-03-7
- Chemical Name
- Alcuronium Chloride
- Synonyms
- Alcuronium;Alcuronium dichloride;Alcuronium chloride CRS;Alcuronium Chloride USP/EP/BP;N,N′-Diallylnortoxiferinium dichloride
- CBNumber
- CB6875035
- Molecular Formula
- C44H50N4O2.2Cl
- Formula Weight
- 737.811
- MOL File
- 15180-03-7.mol
Alcuronium Chloride Property
- alpha
- D22 -348° (methanol)
Safety
- RIDADR
- 3249
- HazardClass
- 6.1(a)
- PackingGroup
- II
N-Bromosuccinimide Price
- Product number
- A0325200
- Product name
- Alcuronium chloride
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- a0325200
- Price
- $220
- Updated
- 2024/03/01
- Product number
- A514585
- Product name
- AlcuroniumDichloride
- Packaging
- 2.5mg
- Price
- $165
- Updated
- 2021/12/16
Alcuronium Chloride Chemical Properties,Usage,Production
Originator
Alloferin, Roche ,UK ,1966
Uses
Alcuronium Dichloride exists as a neuromuscular blocking agent with ganglion blocking activity. Binds to muscarinic M2 receptors.
Definition
ChEBI: Alcuronium chloride is chloride salt of alcuronium. It contains an alcuronium.
Manufacturing Process
31 g of diallylnortoxiferine diiodide are suspended in 1 liter of water and shaken with 1,100 ml of Amberlite IRA-400 [chloride ion form, described Merck Index, 7th edition, Merck and Co., Inc., Rahway, New Jersey (1960), page 1584], for 2 hours. The diiodide thereby goes into solution. The ion exchanger is filtered off and then washed in 3 portions with a total of 1 liter of water. The combined filtrates are then allowed to run through a column of 300 ml of Amberlite IRA-400 (chloride ion form), rinsed with 300 ml of water and the eluate evaporated to dryness in a vacuum while excluding air. The residue gives on recrystallization from methanol/ethanol crystalline pure colorless diallylnortoxiferine dichloride in a yield of 18.6 g. The compound contains 5 mols of water of crystallization after equilibration in air.
brand name
Alloferin (Hoffmann-LaRoche-International).
Therapeutic Function
Muscle relaxant