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Beclobrate

Product Name
Beclobrate
CAS No.
55937-99-0
Chemical Name
Beclobrate
Synonyms
Turec;Beclipur;Sgd-24774;Beclobrate;Beclobrate USP/EP/BP;Ethyl 2-(4-(4-chlorobenzyl)phenoxy)-2-Methylbutanoate;Ethyl(±)-2-[[α(-(4-chlorophenyl)-4-tolyl]oxy]-2-methylbutyrate;2-[4-(4-Chlorobenzyl)phenoxy]-2-methylbutyric acid ethyl ester;Butanoic acid, 2-[4-[(4-chlorophenyl)Methyl]phenoxy]-2-Methyl-, ethyl ester
CBNumber
CB6875424
Molecular Formula
C20H23ClO3
Formula Weight
346.85
MOL File
55937-99-0.mol
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Beclobrate Property

Boiling point:
bp0.01-0.1 200-204°
storage temp. 
2-8°C
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Safety

Toxicity
LD50 orally in mice: 8000 mg/kg (Thiele, 1979)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0001599
Product name
BECLOBRATE
Purity
95.00%
Packaging
100MG
Price
$1030.84
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0001599
Product name
BECLOBRATE
Purity
95.00%
Packaging
1G
Price
$1904.7
Updated
2021/12/16
Crysdot
Product number
CD31001475
Product name
Beclobrate
Purity
95+%
Packaging
1g
Price
$947
Updated
2021/12/16
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Beclobrate Chemical Properties,Usage,Production

Description

Beclobrate is a hypolipidemic agent related structurally to clofibrate. It is reportedly useful in types IIa-V hyperlipoproteinemias, promoting normalization of t h e atherogenic index.

Originator

Siegfried AG (Switzerland)

Definition

ChEBI: Beclobrate is a diarylmethane.

Manufacturing Process

87.0 g (0.4 mol) of 4-chloro-4'-hydroxydiphenylmethane are heated together with 27.0 g (0.2 mol) of anhydrous potassium carbonate in 350 ml of anhydrous xylene for 30 min to reflux temperature, whereafter a solution of 83.5 g (0.4 mol) of 2-bromo-2-ethyl-2-methyl acetic acid ethyl ester in 50 ml of anhydrous xylene is added. The mixture is kept for 24 hours and with vigorous stirring at reflux temperature. After filtering off the precipitated potassium bromide and evaporating the solvent in a Buchi rotary evaporator, the residue is taken up in ether and extracted with normal sodium hydroxide solution. The ether extracts are washed with water, dried over MgSO4 and concentrated by evaporation. The brown oil (82.0 g) thereby obtained is dissolved in n-hexane and filtered through a column of 200 g of basic Al2O3. After evaporating the solvent and distillation at reduced pressure, 34.7 g of pure ethyl (+/-)-2-((α-(p-chlorophenyl)-p-tolyl)oxy)-2-methylbutyrate are obtained with the boiling point 200-204°C/0.01-0.1 mm Hg.

brand name

BECLOSCLERIN

Therapeutic Function

Antihyperlipidemic

World Health Organization (WHO)

Beclobrate, an antihyperlipidaemic agent, was introduced into medicine in 1985. Although a causal relationship between the use of the drug and hepatic toxicity has not been established, the Intercantonal Office for the Control of Medicines has withdrawn marketing authorization since safer therapeutic alternatives are available. Beclobrate is not registered elsewhere.

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Beclobrate Suppliers

Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Aikon International Limited
Tel
025-66113011 18112977050
Fax
(5)02557626880
Email
cb6@aikonchem.com
Country
China
ProdList
15494
Advantage
58
Angel Pharmatech, Ltd.
Tel
17317130613
Fax
QQ3358272972
Email
3358272972@qq.com
Country
China
ProdList
3249
Advantage
58
Chengdu Saint - Kay Biotechnology Co., Ltd.
Tel
028-85157043 15882256948
Email
676046971@qq.com
Country
China
ProdList
4390
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32063
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
7724
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62163
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24648
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
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View Lastest Price from Beclobrate manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Beclobrate 55937-99-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-11

55937-99-0, BeclobrateRelated Search:


  • Beclobrate
  • Beclipur
  • Ethyl(±)-2-[[α(-(4-chlorophenyl)-4-tolyl]oxy]-2-methylbutyrate
  • Sgd-24774
  • Turec
  • 2-[4-(4-Chlorobenzyl)phenoxy]-2-methylbutyric acid ethyl ester
  • Butanoic acid, 2-[4-[(4-chlorophenyl)Methyl]phenoxy]-2-Methyl-, ethyl ester
  • Ethyl 2-(4-(4-chlorobenzyl)phenoxy)-2-Methylbutanoate
  • Beclobrate USP/EP/BP
  • 55937-99-0
  • C20H23ClO3