alpha-2-pyridylpyridine-2-methanol
- Product Name
- alpha-2-pyridylpyridine-2-methanol
- CAS No.
- 35047-29-1
- Chemical Name
- alpha-2-pyridylpyridine-2-methanol
- Synonyms
- Di(2-pyridyl)methanol;Bis(2-pyridyl)methanol;Di(pyridin-2-yl)Methanol;α-2-pyridylpyridine-2-methanol;α-(2-Pyridinyl)-2-pyridinemethanol;2-Pyridinemethanol, α-2-pyridinyl-;2,2'-(Hydroxymethylene)bispyridine;alpha-2-pyridylpyridine-2-methanol;2-PyridineMethanol, alpha-2-pyridinyl-
- CBNumber
- CB6880396
- Molecular Formula
- C11H10N2O
- Formula Weight
- 186.21
- MOL File
- 35047-29-1.mol
alpha-2-pyridylpyridine-2-methanol Property
- storage temp.
- 2-8°C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 4216BA
- Product name
- Di(pyridin-2-yl)methanol
- Packaging
- 250mg
- Price
- $404
- Updated
- 2021/12/16
- Product number
- CHM0384211
- Product name
- ALPHA-2-PYRIDYLPYRIDINE-2-METHANOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.15
- Updated
- 2021/12/16
- Product number
- 4216BA
- Product name
- Di(pyridin-2-yl)methanol
- Packaging
- 1g
- Price
- $728
- Updated
- 2021/12/16
- Product number
- 4216BA
- Product name
- Di(pyridin-2-yl)methanol
- Packaging
- 5g
- Price
- $2085
- Updated
- 2021/12/16
- Product number
- A235531
- Product name
- Di(pyridin-2-yl)methanol
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $65
- Updated
- 2021/12/16
alpha-2-pyridylpyridine-2-methanol Chemical Properties,Usage,Production
Synthesis
1121-60-4
109-04-6
35047-29-1
The general procedure for the synthesis of bis(pyridin-2-yl)methanol from pyridine-2-carbaldehyde and 2-bromopyridine is as follows: Step A - Synthesis of di(pyridin-2-yl)methanol: To a solution of 2-bromopyridine (3.0 g, 19.0 mmol) in 60 mL of THF was slowly added n-butyllithium (2.5 M in hexane, 7.6 mL, 19.0 mmol) at -78 °C. The reaction mixture was stirred at -78 °C for about 15 min, then pyridine-2-carbaldehyde (2.17 mL, 22.8 mmol) was added slowly dropwise at the same temperature. After the dropwise addition was completed, stirring was continued at -78 °C for 30 min, then gradually warmed up to room temperature and stirred for 2 hours. Upon completion of the reaction, the reaction was quenched with saturated aqueous NH4Cl solution. The reaction mixture was diluted with ethyl acetate and the organic layer was separated and the aqueous layer was back-extracted twice with ethyl acetate. All organic phases were combined, washed with brine, dried over anhydrous magnesium sulfate, filtered, and concentrated under reduced pressure to give bis(pyridin-2-yl)methanol in 70% yield as a yellow oil.
References
[1] Synlett, 2006, # 16, p. 2553 - 2558
[2] Synlett, 2008, # 9, p. 1418 - 1422
[3] Patent: WO2008/130581, 2008, A1. Location in patent: Page/Page column 181
[4] Journal of Organic Chemistry, 1993, vol. 58, # 16, p. 4382 - 4388
alpha-2-pyridylpyridine-2-methanol Preparation Products And Raw materials
Raw materials
Preparation Products
alpha-2-pyridylpyridine-2-methanol Suppliers
- Tel
- 025-58196018 800028039
- Fax
- 025-83453306
- sales@fartop.net
- Country
- China
- ProdList
- 2229
- Advantage
- 55
- Tel
- 15026594951
- Fax
- 0556-5030632
- rs@raise-chem.com
- Country
- China
- ProdList
- 4454
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 021-34625901 18018851262;
- 420970979@qq.com
- Country
- China
- ProdList
- 5894
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- +1-5166625404;
- Fax
- 1-516-927-0118
- Info@alfa-chemistry.com
- Country
- United States
- ProdList
- 20405
- Advantage
- 58
- Tel
- 0371-0371-53736046 13393710386
- Fax
- QQ:2853979814
- 2853979814@qq.com
- Country
- China
- ProdList
- 9948
- Advantage
- 58
- Tel
- 2383948258 19172820304
- 2383948258@qq.com
- Country
- China
- ProdList
- 12987
- Advantage
- 58
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29757
- Advantage
- 58
- Tel
- 400-6005915
- sales@picasso-e.com
- Country
- China
- ProdList
- 39653
- Advantage
- 58