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4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone

Product Name
4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone
CAS No.
43076-30-8
Chemical Name
4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone
Synonyms
Terfenadine EP Impurity A;Terfenadine impurity A CRS;Terfenadine USP Related Compound A;4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone;1-(4-TERT-BUTYLPHENYL)-4-[4-(ALPHA-HYDROXYBENZHYDRYL)PIPERIDINO]BUTAN-1-ONE;1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-one;1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-one;1-Butanone, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-;1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-one (Terfenadone)
CBNumber
CB6884031
Molecular Formula
C32H39NO2
Formula Weight
469.66
MOL File
43076-30-8.mol
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4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone Property

Melting point:
175 °C
Boiling point:
624.5±55.0 °C(Predicted)
Density 
1.082±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
13.32±0.29(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T0080000
Product name
Terfenadine impurity A
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
t0080000
Price
$223
Updated
2024/03/01
TRC
Product number
T114505
Product name
Terfenadone
Packaging
100mg
Price
$180
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0019430
Product name
TERFENADONE
Purity
95.00%
Packaging
5MG
Price
$495.08
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
61901
Product name
Terfenadone
Packaging
250mg
Price
$650
Updated
2021/12/16
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4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone Chemical Properties,Usage,Production

Uses

Terfenadone, is the first nonsedating antihistamine for the treatment of allergic rhinitis. It is also the derivative of Terfenadine (T114500). Terfenadine, has been also identified to be an inhibitor of human CD81-receptor HCV-E2 interaction.

4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone Suppliers

Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
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View Lastest Price from 4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Terfenadone 43076-30-8
Price
US $1.00-22.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100000KG
Release date
2024-08-23

43076-30-8, 4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenoneRelated Search:


  • 4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone
  • 1-(4-TERT-BUTYLPHENYL)-4-[4-(ALPHA-HYDROXYBENZHYDRYL)PIPERIDINO]BUTAN-1-ONE
  • 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-one
  • 1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-one
  • Terfenadine impurity A CRS
  • 1-Butanone, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-
  • Terfenadine USP Related Compound A
  • Terfenadine EP Impurity A
  • 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-one (Terfenadone)
  • 43076-30-8