elliptinium acetate
- Product Name
- elliptinium acetate
- CAS No.
- 58337-35-2
- Chemical Name
- elliptinium acetate
- Synonyms
- H9m2E;Elliptinium;Ellipticine analog;elliptinium acetate;Ellipticine acetomethylate;NSC 264137|||Celiptium|||NSC 264137;2-Methyl-9-hydroxyellipticinium acetate;9-Hydroxy-2-methylellipticinium acetate;N2-Methyl-9-hydroxyellipticinium acetate;2,5,11-trimethyl-6H-pyrido[4,3-b]carbazol-2-ium-9-ol:acetate
- CBNumber
- CB6884602
- Molecular Formula
- C20H20N2O3
- Formula Weight
- 336.3844
- MOL File
- 58337-35-2.mol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- API0011308
- Product name
- ELLIPTINIUM ACETATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.26
- Updated
- 2021/12/16
elliptinium acetate Chemical Properties,Usage,Production
Uses
Elliptinium acetate (NSC 264137) is a DNA intercalating agent that is highly cytotoxic to L1 210 cells and covalently binds to nucleic acids from L1210 cells. Elliptinium acetate can be used in cancer research, particularly in metastatic breast cancer[1][2].
Anticancer Research
It is an ellipticine derivative and is obtained from Bleekeria vitensis, a Fijian medicinalplant. It is used to treat breast cancer (Shoeb 2006).
References
[1] Dugue B, et al. Covalent binding of elliptinium acetate (NSC 264137) to nucleic acids of L1210 cells in culture. Cancer Res. 1986 Aug;46(8):3828-33. PMID:2425935
[2] Arteaga CL, et al. Elliptinium, a DNA intercalating agent with broad antitumor activity in a human tumor cloning system. Eur J Cancer Clin Oncol. 1987 Nov;23(11):1621-6. DOI:10.1016/0277-5379(87)90440-8
elliptinium acetate Preparation Products And Raw materials
Raw materials
Preparation Products
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