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cropropamide

Product Name
cropropamide
CAS No.
633-47-6
Chemical Name
cropropamide
Synonyms
cropropamide;(E)-N-[1-(Dimethylcarbamoyl)propyl]-N-propyl-but-2-enamide;N-[1-[(Dimethylamino)carbonyl]propyl]-N-propyl-2-butenamide;2-ButenaMide, N-[1-[(diMethylaMino)carbonyl]propyl]-N-propyl-
CBNumber
CB6920852
Molecular Formula
C13H24N2O2
Formula Weight
240.34
MOL File
633-47-6.mol
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cropropamide Property

Boiling point:
bp0.25 128-130°
Density 
0.977±0.06 g/cm3(Predicted)
storage temp. 
Amber Vial, Refrigerator
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Soluble)
pka
-0.74±0.70(Predicted)
form 
Oil
color 
Pale Yellow to Dark Yellow
Stability:
Light Sensitive
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
163208
Product name
Cropropamide
Packaging
50mg
Price
$460
Updated
2021/12/16
TRC
Product number
C815020
Product name
Cropropamide
Packaging
100mg
Price
$650
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD156958
Product name
(E)-N-[1-(Dimethylcarbamoyl)propyl]-N-propyl-but-2-enamide
Packaging
250mg
Price
$1100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD156958
Product name
(E)-N-[1-(Dimethylcarbamoyl)propyl]-N-propyl-but-2-enamide
Packaging
500mg
Price
$1800
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD156958
Product name
(E)-N-[1-(Dimethylcarbamoyl)propyl]-N-propyl-but-2-enamide
Packaging
1g
Price
$3000
Updated
2021/12/16
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cropropamide Chemical Properties,Usage,Production

Originator

Cropropamide,Geigy (Novartis)

Uses

Cropropamide, is the main component of the drug Prethcamide, which is a respiratory stimulant.

Definition

ChEBI: Cropropamide is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.

Manufacturing Process

2-Chlorbutiric acid dimethyl amide are dissolved in absolute benzene and heated to 110°C with propylamine in the autoclave. After cooling the propylamine hydrochloride is filtered off, then the benzene solution is treated with water and freed from any dissolved propylamine hydrochloride by means of potassium lye. After distillation of the benzene the 2-propylaminobutyric acid dimethyl amide is rectified in vacuum.
2-Propylaminobutyric acid dimethyl amide is dissolved in benzene and while cooling, crotonic acid chloride is added and mixed. Then, reaction mixture is filtered and freed from benzene to give 2-(N-propyl-crotonylamido)butyric acid dimethyl amide, melting point 128°-130°C.

Therapeutic Function

Respiratory stimulant

cropropamide Preparation Products And Raw materials

Raw materials

Preparation Products

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cropropamide Suppliers

Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80

633-47-6, cropropamideRelated Search:


  • cropropamide
  • N-[1-[(Dimethylamino)carbonyl]propyl]-N-propyl-2-butenamide
  • 2-ButenaMide, N-[1-[(diMethylaMino)carbonyl]propyl]-N-propyl-
  • (E)-N-[1-(Dimethylcarbamoyl)propyl]-N-propyl-but-2-enamide
  • 633-47-6