clopenthixol

Product Name: clopenthixol
CAS No.: 982-24-1
Chemical Name: clopenthixol
Synonyms: N-746;AY-62021;Sordinol;NSC-64087;Neo-ciatyl;Aids115500;Aids-115500;clopenthixol;CHLORPENTHIXOL;clopenthixol USP/EP/BP
CBNumber: CB6924052
Molecular Formula: C22H25ClN2OS
Formula Weight: 400.96
MOL File: 982-24-1.mol

More

Less

clopenthixol Property

Boiling point:: 577.4±50.0 °C(Predicted)
Density: 1.289±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: pKa 6.69 (Uncertain)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0010988
Product name: CHLORPENTHIXOL
Purity: 95.00%
Packaging: 5MG
Price: $500.58
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0010988
Product name: CHLORPENTHIXOL
Purity: 95.00%
Packaging: 1G
Price: $2804.55
Updated: 2021/12/16

Crysdot

Product number: CD31000026
Product name: trans-Clopenthixol
Purity: 95+%
Packaging: 1g
Price: $1424
Updated: 2021/12/16

More

Less

clopenthixol Chemical Properties,Usage,Production

Chemical Properties

Colorless paste. Soluble in methanol, insoluble in ether. cis(Z)-configuration: [53772-83-1]. Crystallized, melting point 84-85°C. Clopenthixol Dihydrochloride: C22H25C1N2OS?2HCl.[633-59-0]. Crystallized from ethanol, melting point 250~260°C (decomposition). Extremely soluble in water, insoluble in alcohol, several insoluble in other organic solvents. Acute toxicity LD50 male mice (mg/kg): 111 IV. cis(Z)-dihydrochloride: [58045-23-1]. Crystalline, melting point 250~260°C (decomposition). Acute toxicity LD50 male mice (mg/kg): 105 IV.

Originator

Ciatyl,Tropon,W. Germany,1961

Uses

Antipsychotic.

Definition

ChEBI: A thioxanthene derivative having a chloro substituent at the 2-position and an alkylidene group at the 10-position with undefined double bond stereochemistry.

Manufacturing Process

A mixture of 31 5 g (0.1 mol) of 2-chloro-9-(3'-dimethylaminopropylidene)- thiaxanthene (MP 97°C) and 100 g of N-(β-hydroxyethyl)piperazine is heated to 130°C and boiled under reflux at this temperature for 48 hours. After cooling,the excess of N-(β-hydroxyethyl)piperazine is evaporated in vacuo, and the residue is dissolved in ether. The ether phase is washed with water and extracted with dilute acetic acid, and 2-chloro-9-[3'-N-(N'-β- hydroxyethyl)piperazinylpropylidene]-thiaxanthene separated from the aqueous acetic acid solution by addition of dilute sodium hydroxide solution to basic reaction. The free base is extracted with ether, the ether phase dried over potassium carbonate, the ether evaporated and the residue dissolved in absolute ethanol. By complete neutralization of the ethanolic solution with a solution of dry hydrogen chloride in absolute ethanol, the dihydrochloride of 2- chloro-9-[3'-N-(N'-β-hydroxyethyl)piperazinylpropylidene]-thiaxanthene is produced and crystallizes out as a white substance melting at about 250°C to 260°C with decomposition. The yield is 32 g.

Therapeutic Function

Antipsychotic

clopenthixol Preparation Products And Raw materials

Raw materials

Epoxy 2-Chlorothioxanthone Piperazine Allyl bromide Diallyl sulfide

Preparation Products

More

Less

clopenthixol Suppliers

China 13 Europe 2 Germany 1 India 1 United States 4 Global 21

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Shanghai Botuo Biotechnology Co., LTD

Tel: 16621358918
Fax: QQ:402135374
Email: botuopharma888@163.com
Country: China
ProdList: 9208
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Tachizaki Biomedical Research Center

Tel: 18014399201
Email: sales@chemlab-tachizaki.com
Country: China
ProdList: 2742
Advantage: 58

Baoji Didu Pharmaceutical and Chemical Co., Ltd

Tel: 029-81145305 17791533577
Email: 1021@dideu.com
Country: China
ProdList: 10009
Advantage: 58

Tanmo Quality Inspection Technology Co., Ltd.

Tel: 4008-099-669
Email: 23419001name@qq.com
Country: CHINA
ProdList: 6043
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 13308200041
Email: 2851167782@qq.com
Country: China
ProdList: 11146
Advantage: 58

More

Less

View Lastest Price from clopenthixol manufacturers

Dideu Industries Group Limited

Product: clopenthixol 982-24-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-23

982-24-1, clopenthixol Related Search:

Chlorprothixene clopenthixol decanoate Zuclopenthixol acetate cis-Clopenthixol Clopenthixol Hydrochloride Clopenthixol-Cis(Z) trans-Clopenthixol clopenthixol Prothixene CLOPENTHIXOL DIHYDROCHLORIDE

2-(4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)piperazin-1-yl)ethanol

clopenthixol

CHLORPENTHIXOL

4-[3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl]-1-piperazineethanol

AY-62021

N-746

Neo-ciatyl

NSC-64087

1-Piperazineethanol, 4-(3-(2-chloro-9H-thioxanthen-9-ylidene)propyl)-

Aids115500

Aids-115500

Sordinol

Zuclopenthixol (Clopenthixol)

Zuclopenthixol (cis+trans)

Zuclopenthixol (Clopenthixol) (Mixture of Z and E Isomers)

clopenthixol USP/EP/BP

ClopenthixolQ: What is Clopenthixol Q: What is the CAS Number of Clopenthixol Q: What is the storage condition of Clopenthixol

Zuclopenthixol (cis+trans) in methanol

982-24-1