ChemicalBook > CAS DataBase List > bunaftine
bunaftine
- Product Name
- bunaftine
- CAS No.
- 32421-46-8
- Chemical Name
- bunaftine
- Synonyms
- Meregon;bunaftine;Bunaftide;Bunaphtine;Bunaphtide;Bunaphtide|||Meregon|||Bunaftine;N-Butyl-N-[2-(diethylamino)ethyl]-1-naphthalenecarboxamide;N-butyl-N-[2-(diethylamino)ethyl]naphthalene-1-carboxamide;1-Naphthalenecarboxamide, N-butyl-N-[2-(diethylamino)ethyl]-
- CBNumber
- CB6926177
- Molecular Formula
- C21H30N2O
- Formula Weight
- 326.48
- MOL File
- 32421-46-8.mol
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bunaftine Property
- Boiling point:
- bp0.1 178°
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
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Safety
- Toxicity
- LD50 i.p. in mice: 122 mg/kg (Giannini et al.)
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0010880
- Product name
- BUNAFTINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.26
- Updated
- 2021/12/16
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bunaftine Chemical Properties,Usage,Production
Originator
Bunaftine,Malesci
Definition
ChEBI: Bunaftine is a naphthalenecarboxamide.
Manufacturing Process
Into a solution containing α-naphthoic acid chloride in benzene with agitation
and cooling for 0.5 h a benzene solution of N,N-diethylamine-ethyl-N'-(nbutyl)
amine is dropped. As the dropping is ended, the solution is kept under
agitation in a water bath for 3 h.
After cooling the benzene solution is extracted with 10% hydrochloric acid;
then the aqueous solution is saturated with potassium carbonate. The
separated oil is extracted with ether and, after drying on sodium sulfate, the
solvent is removed and the residue is vacuum distilled. So the N-(2-
diethylamino-ethyl)-N-(n-butyl)-1-naphthalenecarboxamide, boiling point
178°C/0.1 mm/Hg.
Therapeutic Function
Antiarrhythmic
bunaftine Preparation Products And Raw materials
Raw materials
Preparation Products
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