5-(Trifluoromethyl)-1-indanone

Product Name: 5-(Trifluoromethyl)-1-indanone
CAS No.: 150969-56-5
Chemical Name: 5-(Trifluoromethyl)-1-indanone
Synonyms: 5-trifluormethyl-1-indanone;5-(TRIFLUOROMETHYL)INDANONE;5-(Trifluoromethyl)-1-indanone;5-(Trifluoromethyl)indan-1-one 98%;5-(TRIFLUOROMETHYL)-2,3-DIHYDROINDEN-1-ONE,98%;5-(TrifluoroMethyl)-2,3-dihydro-1H-inden-1-one;1H-Inden-1-one, 2,3-dihydro-5-(trifluoromethyl)-;2,3-Dihydro-5-(trifluoromethyl)-1H-inden-1-one, 2,3-Dihydro-1-oxo-5-(trifluoromethyl)-1H-indene
CBNumber: CB6948238
Molecular Formula: C10H7F3O
Formula Weight: 200.16
MOL File: 150969-56-5.mol

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5-(Trifluoromethyl)-1-indanone Property

Boiling point:: 237.1±40.0 °C(Predicted)
Density: 1.347±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), DMSO (Slightly)
form: Solid
color: White to Off-White

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Safety

HS Code: 2914390090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T899625
Product name: 5-(Trifluoromethyl)-1-indanone
Packaging: 50mg
Price: $90
Updated: 2021/12/16

Apolloscientific

Product number: PC8805
Product name: 5-(Trifluoromethyl)indan-1-one
Purity: 98%
Packaging: 250mg
Price: $108
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2817-3-06
Product name: 5-(Trifluoromethyl)indan-1-one
Packaging: 250mg
Price: $173
Updated: 2021/12/16

AK Scientific

Product number: U514
Product name: 5-(Trifluoromethyl)-1-indanone
Packaging: 250mg
Price: $197
Updated: 2021/12/16

Apolloscientific

Product number: PC8805
Product name: 5-(Trifluoromethyl)indan-1-one
Purity: 98%
Packaging: 1g
Price: $268
Updated: 2021/12/16

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5-(Trifluoromethyl)-1-indanone Chemical Properties,Usage,Production

Synthesis

869725-56-4

150969-56-5

Step E General procedure for the synthesis of 5-(trifluoromethyl)indan-1-one from 3-[2-bromo-5-(trifluoromethyl)phenyl]propionic acid: to a mixture of 3-[2-bromo-5-(trifluoromethyl)phenyl]propionic acid (2.8 g, 9.4 mmol) in THF (100 mL) and hexanes (20 mL) was added slowly and dropwise at -78°C a solution of 2.5 M n-butyllithium in hexane (8.3 mL). After dropwise addition, the reaction was quenched with saturated aqueous NH4Cl solution. The reaction mixture was extracted twice with ethyl acetate. The combined organic phases were washed with saturated aqueous NaHCO3 and brine, dried over anhydrous MgSO4 and concentrated. The crude product was purified by fast column chromatography on silica gel with 10-20% EtOAc/hexane as eluent to afford the target product 5-(trifluoromethyl)indan-1-one as a white solid (0.7 g, 37% yield).LC/MS analysis: the calculated value of (M+H)+ for C10H7F3O was 201; measured value, 201.1.

References

[1] Patent: US2005/261310, 2005, A1. Location in patent: Page/Page column 25
[2] ACS Medicinal Chemistry Letters, 2010, vol. 1, # 9, p. 483 - 487

5-(Trifluoromethyl)-1-indanone Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(Trifluoromethyl)-1-indanone Suppliers

China 77 Germany 1 India 2 United Kingdom 1 United States 10 Global 91

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View Lastest Price from 5-(Trifluoromethyl)-1-indanone manufacturers

Career Henan Chemical Co

Product: 5-(Trifluoromethyl)-1-indanone 150969-56-5
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2019-12-24

150969-56-5, 5-(Trifluoromethyl)-1-indanoneRelated Search:

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5-(TRIFLUOROMETHYL)-2,3-DIHYDROINDEN-1-ONE,98%

5-(TRIFLUOROMETHYL)INDANONE

5-trifluormethyl-1-indanone

5-(Trifluoromethyl)-1-indanone

2,3-Dihydro-5-(trifluoromethyl)-1H-inden-1-one, 2,3-Dihydro-1-oxo-5-(trifluoromethyl)-1H-indene

5-(TrifluoroMethyl)-2,3-dihydro-1H-inden-1-one

5-(Trifluoromethyl)indan-1-one 98%

1H-Inden-1-one, 2,3-dihydro-5-(trifluoromethyl)-

150969-56-5

C10H7OF3

Indanone & Indene