ChemicalBook > CAS DataBase List > SB 224289 HYDROCHLORIDE

SB 224289 HYDROCHLORIDE

Product Name
SB 224289 HYDROCHLORIDE
CAS No.
180084-26-8
Chemical Name
SB 224289 HYDROCHLORIDE
Synonyms
SB 224289A;1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine] hydrochloride;(2'-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)(1'-methyl-6,7-dihydrospiro[furo[2,3-f]indole-3,4'-piperidin]-5(2H)-yl)methanone hydrochloride;(2'-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)(1'-methyl-6,7-dihydrospiro[furo[2,3-f]indole-3,4'-piperidin]-5(2H)-yl)methanone hydrochloride;SB-224289A, 1μ-Methyl-5-[[2μ-methyl-4μ-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4μ-piperidine] hydrochloride
CBNumber
CB6972578
Molecular Formula
C32H32N4O3HCl
Formula Weight
0
MOL File
180084-26-8.mol
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SB 224289 HYDROCHLORIDE Property

storage temp. 
Store at RT
solubility 
Soluble to 10 mM in DMSO with gentle warming
form 
Powder
color 
White to off-white
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Safety

Safety Statements 
22-24/25
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17036
Product name
SB-224289 (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
17036
Product name
SB-224289 (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
17036
Product name
SB-224289 (hydrochloride)
Purity
≥98%
Packaging
25mg
Price
$208
Updated
2024/03/01
Cayman Chemical
Product number
17036
Product name
SB-224289 (hydrochloride)
Purity
≥98%
Packaging
50mg
Price
$301
Updated
2024/03/01
TRC
Product number
S155015
Product name
SB-224289Hyrochloride
Packaging
10mg
Price
$240
Updated
2021/12/16
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SB 224289 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

SB 224289A is a 5-HT1B antagonist.

Uses

SB-224289 Hydrochloride is a selective SR-1B antagonist; 5-HT1B antagonist.

Definition

ChEBI: SB 224289 hydrochloride is a hydrochloride that is the monohydrochloride salt of SB 224289. Selective 5-HT1B receptor antagonist (pKi = 8.2). Displays >60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. Centrally active following oral administration in vivo. It has a role as a prodrug and a serotonergic antagonist. It contains a SB 224289(1+).

storage

Room temperature

SB 224289 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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SB 224289 HYDROCHLORIDE Suppliers

Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71

180084-26-8, SB 224289 HYDROCHLORIDERelated Search:


  • 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine] hydrochloride
  • SB-224289A, 1μ-Methyl-5-[[2μ-methyl-4μ-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4μ-piperidine] hydrochloride
  • SB 224289A
  • (2'-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)(1'-methyl-6,7-dihydrospiro[furo[2,3-f]indole-3,4'-piperidin]-5(2H)-yl)methanone hydrochloride
  • (2'-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)(1'-methyl-6,7-dihydrospiro[furo[2,3-f]indole-3,4'-piperidin]-5(2H)-yl)methanone hydrochloride
  • 180084-26-8
  • C32H32N4O3HCl