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CIPROXIFAN

Product Name
CIPROXIFAN
CAS No.
184025-19-2
Chemical Name
CIPROXIFAN
Synonyms
CS-109;CIPROXIFAN;FUB359 Maleate;FUB-359 Maleate;FUB 359 Maleate;Ciproxifan Moleate;FUB 359 Maleate salt;Ciproxifan maleate, >=98%;Ciproxifan Maleate (FUB-359);Ciproxifan maleate(FUB-359 maleate)
CBNumber
CB6972679
Molecular Formula
C16H18N2O2.C4H4O4
Formula Weight
386.402
MOL File
184025-19-2.mol
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CIPROXIFAN Property

storage temp. 
Store at -20°C
solubility 
DMSO: soluble32mg/mL
form 
powder
color 
white to beige
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-43
Safety Statements 
26-36/37/39
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C6848
Product name
Ciproxifan maleate
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$211
Updated
2024/03/01
Sigma-Aldrich
Product number
C6848
Product name
Ciproxifan maleate
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$732
Updated
2024/03/01
Cayman Chemical
Product number
29513
Product name
Ciproxifan (maleate)
Packaging
5mg
Price
$120
Updated
2024/03/01
Cayman Chemical
Product number
29513
Product name
Ciproxifan (maleate)
Packaging
25mg
Price
$435
Updated
2024/03/01
Cayman Chemical
Product number
29513
Product name
Ciproxifan (maleate)
Packaging
1mg
Price
$33
Updated
2024/03/01
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CIPROXIFAN Chemical Properties,Usage,Production

Description

Ciproxifan is a histamine H3 receptor antagonist (Ki = 0.5 nM for inhibition of histamine release in rat synaptosomal preparations). It is selective for histamine H3 over histamine H1 and H2, M3 muscarinic, and α1D- and β1-adrenergic receptors (Kis = 3.15-25 μM), as well as the serotonin (5-HT) receptor subtypes 5-HT1B, 5-HT2A, 5-HT3, and 5-HT4 (Kis = 1.58-15 μM) in radioligand binding assays. Ciproxifan (3-300 nM) inhibits relaxation in precontracted isolated guinea pig ileal longitudinal muscle induced by R-(–)-α-methylhistamine . In vivo, ciproxifan reduces R-(–)-α-methylhistamine-induced water consumption in rats (ED50 = 0.09 mg/kg). It increases wake episode duration and latency to fall asleep in rats when administered at a dose of 2 mg/kg.

Uses

Ciproxifan is a potent histamine H3 receptor antagonist which affects histamine levels in the brain. It may be used in treatments for sleep and neurological disorders.

Biochem/physiol Actions

Potent, selective H3 histamine receptor antagonist.

CIPROXIFAN Preparation Products And Raw materials

Raw materials

Preparation Products

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CIPROXIFAN Suppliers

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View Lastest Price from CIPROXIFAN manufacturers

Career Henan Chemical Co
Product
(Z)-but-2-enedioic acid,cyclopropyl-[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone 184025-19-2
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-01-01

184025-19-2, CIPROXIFANRelated Search:

2-Isopropylimidazole

  • Ciproxifan Moleate
  • FUB 359 Maleate
  • FUB359 Maleate
  • FUB-359 Maleate
  • Ciproxifan maleate, >=98%
  • Cyclopropyl (4-[3-(1H-imidazol-4-yl)propyloxy]phenyl) ketone maleate salt
  • (4-(3-(1H-Imidazol-5-yl)propoxy)phenyl)(cyclopropyl)methanone maleate
  • CIPROXIFAN
  • FUB 359 maleate salt, Cyclopropyl (4-[3-(1H-imidazol-4-yl)propyloxy]phenyl) ketone maleate salt
  • FUB 359 Maleate salt
  • Methanone, cyclopropyl[4-[3-(1H-iMidazol-4-yl)propoxy]phenyl]-, (Z)-2-butenedioate (1:1)
  • Cyclopropyl[4-[3-(1H-imidazol-4-yl)propoxy]phenyl]methanone (2Z)-2-butenedioate
  • Ciproxifan Maleate (FUB-359)
  • (Z)-but-2-enedioic acid,cyclopropyl-[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone
  • FUB 359 MALEATE;FUB359 MALEATE;FUB-359 MALEATE
  • Ciproxifan maleate(FUB-359 maleate)
  • CS-109
  • Inhibitor,aging,inhibit,Ciproxifan,disorders,Ciproxifan maleate,FUB359,Histamine Receptor,FUB-359,histamine,Alzheimer's
  • (4-(3-(1H-Imidazol-4-yl)propoxy)phenyl)(cyclopropyl)methanone maleate
  • Ciproxifan maleate, prototypic H3 inverse agonist / antagonist
  • 184025-19-2
  • C16H18N2O2C4H4O4
  • Inhibitors