Pyridine, 2-chloro-4-(chloromethyl)- (9CI)
- Product Name
- Pyridine, 2-chloro-4-(chloromethyl)- (9CI)
- CAS No.
- 101990-73-2
- Chemical Name
- Pyridine, 2-chloro-4-(chloromethyl)- (9CI)
- Synonyms
- 2-chloro-pyridin-4-ylmethyl chloride;Pyridine, 2-chloro-4-(chloromethyl)-;2-Chloro-4-(chloromethyl)pyridine 97%;2-Chloro-4-(chloroMethyl)pyridine, 97+%;Pyridine, 2-chloro-4-(chloromethyl)- (9CI);Pyridine, 2-chloro-4-(chloromethyl)- (9CI) HCL;Pyridine, 2-chloro-4-(chloromethyl)- (9CI) ISO 9001：2015 REACH
- CBNumber
- CB71060057
- Molecular Formula
- C6H5Cl2N
- Formula Weight
- 162.02
- MOL File
- 101990-73-2.mol
Pyridine, 2-chloro-4-(chloromethyl)- (9CI) Property
- Melting point:
- 123-125℃
- Boiling point:
- 51 °C(Press: 0.9 Torr)
- Density
- 1.324
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 0.13±0.10(Predicted)
- form
- liquid
- color
- Pink
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- C609743
- Product name
- 2-Chloro-4-(chloromethyl)pyridine
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- W9907
- Product name
- 2-Chloro-4-(chloromethyl)pyridine
- Packaging
- 1g
- Price
- $29
- Updated
- 2021/12/16
- Product number
- 058839
- Product name
- 2-Chloro-4-chloromethyl-pyridine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $62
- Updated
- 2021/12/16
- Product number
- 3H32-5-CQ
- Product name
- 2-Chloro-4-(chloromethyl)pyridine
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- W9907
- Product name
- 2-Chloro-4-(chloromethyl)pyridine
- Packaging
- 5g
- Price
- $94
- Updated
- 2021/12/16
Pyridine, 2-chloro-4-(chloromethyl)- (9CI) Chemical Properties,Usage,Production
Synthesis
100704-10-7
101990-73-2
Step b) Synthesis of 2-chloro-4-(chloromethyl)pyridine: 11.3 g of (2-chloropyridin-4-yl)methanol obtained in step a) was dissolved in 200 mL of dichloromethane, to which 6.896 mL of thionyl chloride was slowly added, followed by the addition of 2.1 mL of dimethylformamide as catalyst. The reaction mixture was stirred at room temperature for 3 hours. Upon completion of the reaction, 50 mL of water was added slowly and dropwise to quench the reaction. The organic layer was separated, dried with anhydrous magnesium sulfate, filtered to remove the desiccant, and the filtrate was concentrated under reduced pressure to afford 12.8 g (100% yield) of 2-chloro-4-(chloromethyl)pyridine as an amber liquid, which could be used in the subsequent reaction without further purification. Thin layer chromatography (TLC) analysis showed an Rf value of 0.44 (unfolding agent: dichloromethane).
References
[1] Patent: US2009/82329, 2009, A1. Location in patent: Page/Page column 16
[2] Patent: WO2010/7374, 2010, A1. Location in patent: Page/Page column 38-39
[3] Patent: US2011/301122, 2011, A1. Location in patent: Page/Page column 41-42
[4] Patent: US2011/312930, 2011, A1. Location in patent: Page/Page column 44
[5] Patent: US2013/196964, 2013, A1. Location in patent: Paragraph 0967; 0968; 0969; 0970
Pyridine, 2-chloro-4-(chloromethyl)- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Pyridine, 2-chloro-4-(chloromethyl)- (9CI) manufacturers
- Product
- Pyridine, 2-chloro-4-(chloromethyl)- (9CI) 101990-73-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-03
- Product
- Pyridine, 2-chloro-4-(chloromethyl)- (9CI) 101990-73-2
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- Pyridine, 2-chloro-4-(chloromethyl)- (9CI) 101990-73-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-28