Piperazinone, 1-(2-pyridinyl)- (9CI)
- Product Name
- Piperazinone, 1-(2-pyridinyl)- (9CI)
- CAS No.
- 345310-98-7
- Chemical Name
- Piperazinone, 1-(2-pyridinyl)- (9CI)
- Synonyms
- 1-(Pyridin-2-yl);Piperazinone, 1-(2-pyridinyl);1-(2-pyridinyl)-2-piperazinone;2-Piperazinone, 1-(2-pyridinyl)-;1-pyridin-2-yl-piperazin-2-one 2hcl;Piperazinone, 1-(2-pyridinyl)- (9CI);1-(pyridin-2-yl)piperazin-2-one hydrochloride;1-Pyridin-2-yl-piperazin-2-one dihydrochloride;Piperazinone, 1-(2-pyridinyl) 345310-98-7, Piperazinone, 1-(2-pyrimidinyl) 59637-59-1
- CBNumber
- CB71066448
- Molecular Formula
- C9H11N3O
- Formula Weight
- 177.2
- MOL File
- 345310-98-7.mol
Piperazinone, 1-(2-pyridinyl)- (9CI) Property
- Boiling point:
- 432.5±35.0 °C(Predicted)
- Density
- 1.201±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 7.15±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 070109
- Product name
- 1-Pyridin-2-yl-piperazin-2-onedihydrochloride
- Purity
- 98%
- Packaging
- 500mg
- Price
- $643
- Updated
- 2021/12/16
- Product number
- 070109
- Product name
- 1-Pyridin-2-yl-piperazin-2-onedihydrochloride
- Purity
- 98%
- Packaging
- 1g
- Price
- $929
- Updated
- 2021/12/16
- Product number
- CHM0166318
- Product name
- 1-(2-PYRIDINYL)-PIPERAZINONE
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $1284.36
- Updated
- 2021/12/16
- Product number
- CHM0166318
- Product name
- 1-(2-PYRIDINYL)-PIPERAZINONE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1598.52
- Updated
- 2021/12/16
- Product number
- 61-1650
- Product name
- 1-(pyridin-2-yl)piperazin-2-one
- Purity
- 95-98%
- Packaging
- 5g
- Price
- $2850
- Updated
- 2021/12/16
Piperazinone, 1-(2-pyridinyl)- (9CI) Chemical Properties,Usage,Production
Synthesis
374795-58-1
345310-98-7
The general procedure for the synthesis of 1-(2-pyridyl)-piperazinone from the compound (CAS:374795-58-1) was as follows: a slurry of palladium carbon (5%, 3.6 g) in water was added to a solution of palladium carbon containing 4-phenylmethyl-1-(2-pyridyl)piperazin-2-one (3.6 g, 13.48 mmol) and ammonium formate (4.25 g, 67.5 mmol) in a in methanol (100 mL) solution. The mixture was heated to reflux for 4 hours and subsequently cooled to room temperature. The reaction mixture was filtered through a Hyflo TM and the filter cake was washed with methanol. The filtrate was concentrated under reduced pressure to remove the solvent and the resulting residue was purified by fast column chromatography on silica gel, using CH2Cl2/MeOH (90:10) as eluent, to give 1-(2-pyridyl)-piperazinone as an orange oil (1.1 g, 46% yield). Mass spectrometry analysis showed m/z (ES+) 178 ([M+1]+).
References
[1] Patent: US2003/236250, 2003, A1. Location in patent: Page 39
Piperazinone, 1-(2-pyridinyl)- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Piperazinone, 1-(2-pyridinyl)- (9CI) manufacturers
- Product
- 1-(Pyridin-2-yl)piperazin-2-one 345310-98-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- Min98% HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2020-02-12