L-Acetylcarnitine
- Product Name
- L-Acetylcarnitine
- CAS No.
- 3040-38-8
- Chemical Name
- L-Acetylcarnitine
- Synonyms
- C2 carnitine;Acetyl-L-Carnit;Actyl-L-carnitine;L-Acetylcarnitine;(R)-Acetylcarnitine;L-O-Acetylcarnitine;Levocarnitine acetyl;O-acetyl-L-carnitine;L-Acetylcarnitine (hydrochloride)(free base);(3S)-3-acetyloxy-4-trimethylammonio-butanoate
- CBNumber
- CB71073602
- Molecular Formula
- C9H17NO4
- Formula Weight
- 203.24
- MOL File
- 3040-38-8.mol
L-Acetylcarnitine Property
- LogP
- -4.031 (est)
Safety
- Hazardous Substances Data
- 3040-38-8(Hazardous Substances Data)
N-Bromosuccinimide Price
- Product number
- NUT0000483
- Product name
- ACETYL-L-CARNITINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $638.98
- Updated
- 2021/12/16
- Product number
- NUT0000483
- Product name
- ACETYL-L-CARNITINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $876.57
- Updated
- 2021/12/16
L-Acetylcarnitine Chemical Properties,Usage,Production
Description
L-Acetylcarnitine is a endogenous substance, synthesized in the mitochondria, that increases cellular oxidative metabolism and cholinergic activity. It has a good penetration in the CNS when administered orally and intravenously, and no side effects have been observed.
L-Acetylcarnitine has a large variety of interesting pharmacological properties:
It is a cholinergic agent because it promotes the synthesis and freeing of acetylcholine.
It reduces oxidation processes, thus reducing lipofuscin deposits in the brain.
It acts on the hypothalamic-hypophyseal-adrenal axis, antagonizing the existing downregulation (Carta and Calvani 1991).
In a 1-year study of 130 patients with AD (63 in treatment with L-acetylcarnitine and 67 with placebo), an improvement in the cognitive decline measured through neuropsychiatric batteries was observed (Spagnoli et al. 1991).
Uses
Acetylcarnitine may be a useful for treatment of male infertility caused by low quantities of immobile sperm.
Acetyl-L-carnitine (ALC) is produced naturally in humans, and can be found in the brain, liver, and kidneys. ALC is also available as a dietary supplement. ALC has been studied for its potential use in slowing the progression of age-related memory loss and Alzheimer’s disease. ALC may also have a potential use in the treatment of neuropathy (nerve pain) associated with diabetes and HIV disease.
Definition
ChEBI: An O-acyl-L-carnitine where the acyl group specified is acetyl. It facilitates movement of acetyl-CoA into the matrices of mammalian mitochondria during the oxidation of fatty acids.
L-Acetylcarnitine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from L-Acetylcarnitine manufacturers
- Product
- L-Acetylcarnitine 3040-38-8
- Price
- US $10.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 20 Tons
- Release date
- 2021-11-02
- Product
- L-Acetylcarnitine 3040-38-8
- Price
- US $8.00/KG
- Min. Order
- 1g
- Purity
- Min98% HPLC/gc
- Supply Ability
- g/kg/ton
- Release date
- 2020-11-04