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CD1530

Product Name
CD1530
CAS No.
107430-66-0
Chemical Name
CD1530
Synonyms
CD1530;CD1530 >=98% (HPLC);4-(7-(Adamantan-1-yl)-6-hydroxynaphthalen-2-yl)benzoic acid;4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoicacid;Benzoic acid, 4-(6-hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)-
CBNumber
CB71073642
Molecular Formula
C27H26O3
Formula Weight
398.49
MOL File
107430-66-0.mol
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CD1530 Property

Boiling point:
610.7±55.0 °C(Predicted)
Density 
1.290±0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
50 mM in 1 eq. NaOH: Soluble
form 
powder
pka
4.13±0.10(Predicted)
color 
white to beige
InChI
1S/C27H26O3/c28-25-12-22-6-5-21(19-1-3-20(4-2-19)26(29)30)10-23(22)11-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
InChIKey
VCQGNUWOMLYNNG-UHFFFAOYSA-N
SMILES
OC1=CC2=C(C=C(C3=CC=C(C(O)=O)C=C3)C=C2)C=C1C4(C[C@H](C5)C6)C[C@H]6C[C@H]5C4
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Safety

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1759
Product name
CD1530
Purity
≥98% (HPLC)
Packaging
5mg
Price
$112
Updated
2025/07/31
Sigma-Aldrich
Product number
SML1759
Product name
CD1530
Purity
≥98% (HPLC)
Packaging
25mg
Price
$457
Updated
2025/07/31
Cayman Chemical
Product number
19062
Product name
CD1530
Purity
≥98%
Packaging
1mg
Price
$38
Updated
2024/03/01
Cayman Chemical
Product number
19062
Product name
CD1530
Purity
≥98%
Packaging
5mg
Price
$104
Updated
2024/03/01
Cayman Chemical
Product number
19062
Product name
CD1530
Purity
≥98%
Packaging
10mg
Price
$178
Updated
2024/03/01
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CD1530 Chemical Properties,Usage,Production

Uses

CD 1530 is a retinoic acid receptor γ selective agonist. In combination with bexxarotene, they inhibit murine oral-cavity carcinogensis. It is found to inhibit heterotopic ossification and preserve tendon stem cell characteristics. It is also associated with RAR signalling in asthma.

Biological Activity

Potent and selective RAR γ receptor agonist (K i values are 150, 1500 and 2750 nM for RAR γ , RAR β and RAR α receptors respectively). Activates transcriptional activity (AC 50 = 1.8 nM).

in vivo

CD1530 (4 mg/kg; p.o.; once every other day) inhibits FOP-like heterotopic ossification in transgenic mice carrying a Cre-inducible constitutively active ALK2Q207D mutation[1].
CD1530 (2.5 mg/100 mL; p.o., in drinking water; frequency not mentioned; 15 weeks) combined with 4-nitroquinoline 1-oxide reduces the number and severity of tongue tumor lesions in mice with oral cancer[3].
CD1530 (10 μg; local injection; 3 times per week; 3 weeks) accelerates tendon healing in mice with Achilles tendon rupture, inhibits cartilage formation, reduces fibrous tissue-like scar formation, and promotes better collagen fiber alignment[4].
CD1530 (4 mg/kg, p.o.; or 1 mM, intramuscular injection; once a day; administration for 4 weeks) can inhibit muscle fat infiltration, reduce the number of intramuscular adipocytes, and reduce the expression of adipogenic marker genes in mice with rotator cuff tear[6].

Animal Model:C57BL/6 male mice (weight approximately 23 g, 9 weeks old) + rotator cuff tear model[6]
Dosage:4 mg/kg (orally administered); 1 mM (intramuscular injection, solvent: dimethyl sulfoxide)
Administration:Oral administration, once a day, for 4 weeks; Intramuscular injection, once a week, for 4 weeks
Result:Significantly suppressed fatty infiltration in the supraspinatus muscle (p.o.).
Reduced the ratio of the fat area to the muscle cross-sectional area and the expression of adipogenic marker genes Pparg and Cebpa (p.o.).
Reduced fatty infiltration in the supraspinatus muscle (intramuscular injection).

storage

Store at +4°C

CD1530 Preparation Products And Raw materials

Raw materials

Preparation Products

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CD1530 Suppliers

China 39 Germany 1 United Kingdom 1 United States 10 Global 51
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4795
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.
Tel
18081075745
Email
chemflowtech@sina.com
Country
China
ProdList
1886
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32470
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Guangzhou Younan Technology Co., Ltd
Tel
020-82000279 18988941452
Fax
QQ：3283937693
Email
YN_research@163.com
Country
China
ProdList
3000
Advantage
58
ShangHai ChuanQian Chemcial Technique Centre
Tel
15869524721
Email
3525679403@qq.com
Country
China
ProdList
4899
Advantage
58

107430-66-0, CD1530Related Search:

4-(Naphthalen-2-yl)benzoic acid CD1530

  • 4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoicacid
  • Benzoic acid, 4-(6-hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)-
  • CD1530
  • CD1530 >=98% (HPLC)
  • 4-(7-(Adamantan-1-yl)-6-hydroxynaphthalen-2-yl)benzoic acid
  • 107430-66-0