ChemicalBook > CAS DataBase List > Fananserin

Fananserin

Product Name
Fananserin
CAS No.
127625-29-0
Chemical Name
Fananserin
Synonyms
RP-62203;Fananserin;2-[3-[4-(4-Fluorophenyl)piperazino]propyl]-2H-naphth[1,8-cd]isothiazole 1,1-dioxide;2-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide;2-[3-[4-(4-Fluorophenyl)-1-piperazinyl]propyl]-2H-naphthyl[1,8-cd]isothiazole-1,1-dioxide;2H-Naphth[1,8-cd]isothiazole, 2-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-, 1,1-dioxide;Fananserin,Inhibitor,5-HT Receptor,inhibit,5-HT2,RP62203,RP-62203,dopamine,Dopamine Receptor,Serotonin Receptor,5-hydroxytryptamine Receptor
CBNumber
CB71073778
Molecular Formula
C23H24FN3O2S
Formula Weight
425.52
MOL File
127625-29-0.mol
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Fananserin Property

Melting point:
95-97 °C(Solv: acetonitrile (75-05-8))
Boiling point:
641.1±65.0 °C(Predicted)
Density 
1.331±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
Soluble to 100 mM in DMSO
form 
Powder
pka
7.31±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
2645
Product name
Fananserin
Purity
≥99%(HPLC)
Packaging
10
Price
$155
Updated
2021/12/16
Tocris
Product number
2645
Product name
Fananserin
Purity
≥99%(HPLC)
Packaging
50
Price
$558
Updated
2021/12/16
Usbiological
Product number
255281
Product name
Fananserin
Packaging
10mg
Price
$403
Updated
2021/12/16
TRC
Product number
F102368
Product name
Fananserin
Packaging
2.5mg
Price
$165
Updated
2021/12/16
ChemScene
Product number
CS-0024310
Product name
Fananserin
Purity
99.83%
Packaging
5mg
Price
$188
Updated
2021/12/16
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Fananserin Chemical Properties,Usage,Production

Uses

Antipsychotic.

Uses

Fananserin is an antagonist of 5-HT2A.

Definition

ChEBI: LSM-2183 is a sulfonic acid derivative and a member of naphthalenes.

Biological Activity

5-HT 2A receptor antagonist that also displays high affinity at D 4 receptors (K i values are 0.26, 2.93, 25, 38, 70 and 726 nM for 5-HT 2A , D 4 , H 1 , α 1 , 5-HT 1A and D 2 receptors respectively). Inhibits inositol phosphate formation evoked by 5-HT in vitro (IC 50 = 7.76 nM) and antagonizes mescaline-induced head twitches in vivo .

Fananserin Preparation Products And Raw materials

Raw materials

Preparation Products

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Fananserin Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
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Aikon International Limited
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127625-29-0, FananserinRelated Search:


  • 2-[3-[4-(4-Fluorophenyl)piperazino]propyl]-2H-naphth[1,8-cd]isothiazole 1,1-dioxide
  • RP-62203
  • 2-[3-[4-(4-Fluorophenyl)-1-piperazinyl]propyl]-2H-naphthyl[1,8-cd]isothiazole-1,1-dioxide
  • Fananserin
  • 2H-Naphth[1,8-cd]isothiazole, 2-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-, 1,1-dioxide
  • 2-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide
  • Fananserin,Inhibitor,5-HT Receptor,inhibit,5-HT2,RP62203,RP-62203,dopamine,Dopamine Receptor,Serotonin Receptor,5-hydroxytryptamine Receptor
  • 127625-29-0