trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride

Product Name: trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride
CAS No.: 67198-13-4
Chemical Name: trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride
Synonyms: u59900;U50,488;(+/-)-trans-U-50488;(+/-)-U-50488 hydroc;U-50488 mesylate (±)-;Top supplier U58800 U-50488 CAS NO.67198-13-4;2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetami de;N-Methyl-N-[2α-(1-pyrrolidinyl)cyclohexan-1β-yl]-3,4-dichlorophenylacetamide;N-Methyl-N-[(1β,2α)-2-(1-pyrrolidinyl)cyclohexyl]-3,4-dichlorophenylacetamide;3,4-Dichloro-N-methyl-N-[2α-(pyrrolidin-1-yl)cyclohexan-1β-yl]benzeneacetamide
CBNumber: CB71075363
Molecular Formula: C19H26Cl2N2O
Formula Weight: 369.33
MOL File: 67198-13-4.mol

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trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Property

Melting point:: 204-208℃
RTECS: CY1484710
storage temp.: Desiccate at RT

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: U100235
Product name: U50488
Packaging: 1mg
Price: $45
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BRS0000222
Product name: U-50488
Purity: 95.00%
Packaging: 25MG
Price: $970
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BRS0000222
Product name: U-50488
Purity: 95.00%
Packaging: 50MG
Price: $1540
Updated: 2021/12/16

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trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Chemical Properties,Usage,Production

Uses

U 50488 is a selective κ-opioid agonist with analgesic, diuretic, and antitussive properties. κ-opioid agonists are useful compounds to elucidate the functions of κ-receptors in the central nervous system.

Definition

ChEBI: A monocarboxylic acid amide obtained by formal condensation between the carboxy group of 3,4-dichlorophenylacetic acid and the secondary amino group of (1R,2R)-N-methyl-2-(pyrrolidin-1-yl)cyclohexanamine

Biological Activity

Selective κ -opioid agonist. At higher concentrations blocks Na + channels. See separate isomers (trans-(-)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride and 0471 ).

trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Suppliers

China 4 Germany 1 United Kingdom 1 United States 4 Global 10

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
Email: synchempharma@aliyun.com
Country: China
ProdList: 6463
Advantage: 55

Hebei Binshare New Material Co. Ltd

Tel: +8618633865755
Email: china01@hbbinshare.com
Country: CHINA
ProdList: 955
Advantage: 58

Shanghai Universal Biotech Co.,Ltd

Tel: 13774214275
Email: zhouzz@univ-bio.com
Country: China
ProdList: 24990
Advantage: 58

67198-13-4, trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochlorideRelated Search:

(+)-U-50488 HYDROCHLORIDE trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride (-)-(1S,2R)-CIS-3,4-DICHLORO-N-METHYL-N-[2-(1-PYRROLIDINYL)-CYCLOHEXYL]-BENZENEACETAMIDE TARTRATE (+/-)-(5ALPHA,7ALPHA,8BETA)-3,4-DICHLORO-N-METHYL-N-(7-[1-PYRROLIDINYL]-1-OXASPIRO[4.5]DEC-8-YL)BENZENEACETAMIDE MESYLATE

N-Methyl-N-[2α-(1-pyrrolidinyl)cyclohexan-1β-yl]-3,4-dichlorophenylacetamide

(+/-)-trans-U-50488

U50,488

2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetami de

trans-(±)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide mesylate

rel-3,4-Dichloro-N-methyl-N-[(1α*)-2β*-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide

3,4-Dichloro-N-methyl-N-[(1β,2α)-2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide

3,4-Dichloro-N-methyl-N-[2α-(pyrrolidin-1-yl)cyclohexan-1β-yl]benzeneacetamide

N-Methyl-N-[(1β,2α)-2-(1-pyrrolidinyl)cyclohexyl]-3,4-dichlorophenylacetamide

2-(3,4-dichlorophenyl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide

u59900

Top supplier U58800 U-50488 CAS NO.67198-13-4

3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer

U-50488 mesylate (±)-

Benzeneacetamide, 3,4-dichloro-N-methyl-N-[(1R,2R)-2-(1-pyrrolidinyl)cyclohexyl]-, rel-

(+/-)-U-50488 hydroc

67198-13-4

C19H26Cl2N2O

Opioid receptor and opioid-like receptor