ChemicalBook > CAS DataBase List > atamestane
atamestane
- Product Name
- atamestane
- CAS No.
- 96301-34-7
- Chemical Name
- atamestane
- Synonyms
- SH-489;Aconitine Impurity 3;Norgestrel Impurity 2;1-Methylandrosta-1,4-diene-3,17-dione;Androsta-1,4-diene-3,17-dione, 1-methyl-;(8R,9S,10S,13S,14S)-1,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-dione
- CBNumber
- CB71075590
- Molecular Formula
- C20H26O2
- Formula Weight
- 298.42
- MOL File
- 96301-34-7.mol
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atamestane Property
- Melting point:
- 165-167 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
- Boiling point:
- 443.0±45.0 °C(Predicted)
- Density
- 1.12±0.1 g/cm3(Predicted)
- EPA Substance Registry System
- 1-Methylandrosta-1,4-diene-3,17-dione (96301-34-7)
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0005132
- Product name
- ATAMESTANUM
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.14
- Updated
- 2021/12/16
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atamestane Chemical Properties,Usage,Production
Originator
Atamestane,Schering AG
Manufacturing Process
6.01 g of 17β-hydroxy-1-methylandrosta-1,4-dien-3-one is dissolved in 100 ml of acetone. At room temperature, 22 ml of a chromic acid solution (prepared from 6.67 g of CrO3, 6 ml of concentrated sulfuric acid, replenished with water to 100 ml) is added dropwise to this solution. The mixture is stirred for one hour and then precipitated into ice water, the product is suctioned off and dried, thus obtaining after recrystallization from acetone/hexane 5.25 g of 1-methylandrosta-1,4-diene-3,17-dione, melting point 165-166°C.
Therapeutic Function
Aromatase inhibitor
atamestane Preparation Products And Raw materials
Raw materials
Preparation Products
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