BENZO[D]ISOXAZOL-3-OL

Uses

Product Name: BENZO[D]ISOXAZOL-3-OL
CAS No.: 21725-69-9
Chemical Name: BENZO[D]ISOXAZOL-3-OL
Synonyms: benzo[d]isoxazol-3(2H)-one;Benzo[d]isoxazol-3-one;3-HYDROXY-1,2-BENZISOXAZOLE;BUTTPARK 43\57-21;1,2-benzoxazol-3-ol;1,2-benzoxazol-3-one;1,2-benzisoxazol-3-ol;BENZO[D]ISOXAZOL-3-OL;3-HYDROXYBENZISOXAZOLE;1,2-benzisoxazolin-3-one
CBNumber: CB7109586
Molecular Formula: C7H5NO2
Formula Weight: 135.12
MOL File: 21725-69-9.mol

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BENZO[D]ISOXAZOL-3-OL Property

Melting point:: 140-142°C
Density: 1.323±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 13.55±0.20(Predicted)
form: powder
color: Pale orange
CAS DataBase Reference: 21725-69-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
WGK Germany: 3
RTECS: DE4933500
HazardClass: IRRITANT
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H303May be harmfulif swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 760013
Product name: 3-Hydroxybenzisoxazole
Purity: 97%
Packaging: 1g
Price: $37.24
Updated: 2025/07/31

TRC

Product number: B203573
Product name: Benzo[d]isoxazol-3-ol
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR27158
Product name: 3-Hydroxy-1,2-benzisoxazole
Purity: 96%
Packaging: 1g
Price: $32
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H01-1-Y0
Product name: 3-Hydroxy-1,2-benzisoxazole
Packaging: 500mg
Price: $32
Updated: 2021/12/16

Matrix Scientific

Product number: 058596
Product name: Benzo[d]isoxazol-3-ol
Purity: 98%
Packaging: 1g
Price: $41
Updated: 2021/12/16

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BENZO[D]ISOXAZOL-3-OL Chemical Properties,Usage,Production

Uses

benzo[d]isoxazol-3-ol is a useful research chemical.

Definition

ChEBI: Benzo[d]isoxazol-3-ol is a benzisoxazole.

Synthesis

89-73-6

21725-69-9

The general procedure for the synthesis of benzo[D]isoxazol-3-ol from salicylhydroxamic acid is as follows: intermediate 1 (1.92 M in THF solution) was placed in a reaction vial and stirred at 60 °C. CDI (3.84 M, THF solution) was added slowly over 30 minutes. The reaction mixture was heated to reflux and reflux was continued at 60 °C for 2 hours. Upon completion of the reaction, the mixture was cooled to 40 °C and subsequently evaporated to remove the solvent. The residue was quenched with water and the pH was adjusted to 2 with 12 N HCl. The mixture was stirred for 30 min followed by filtration at 10-15 °C to collect the precipitate. The precipitate was washed with ice water and finally dried under reduced pressure at 90 °C to give 3-hydroxybenzisoxazole (Intermediate 2) in quantitative yield.

References

[1] Patent: WO2005/89753, 2005, A2. Location in patent: Page/Page column 27
[2] Tetrahedron Letters, 2016, vol. 57, # 48, p. 5301 - 5303
[3] Tetrahedron: Asymmetry, 1995, vol. 6, # 2, p. 321 - 324
[4] Bulletin of the Chemical Society of Japan, 1983, vol. 56, # 8, p. 2485 - 2489

BENZO[D]ISOXAZOL-3-OL Preparation Products And Raw materials

Raw materials

Preparation Products

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BENZO[D]ISOXAZOL-3-OL Suppliers

Belgium 1 China 108 France 1 Germany 2 India 1 Slovakia 1 United Kingdom 10 United States 19 Global 143

J & K SCIENTIFIC LTD.

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View Lastest Price from BENZO[D]ISOXAZOL-3-OL manufacturers

Career Henan Chemical Co

Product: 3-HYDROXYBENZISOXAZOLE 21725-69-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-08

21725-69-9, BENZO[D]ISOXAZOL-3-OLRelated Search:

6-CHLOROBENZO[D]ISOXAZOL-3-OL BENZO[D]ISOXAZOL-3-OL 7-METHYLBENZO[D]ISOXAZOL-3-OL 3-METHYL-1,2-BENZISOXAZOL-6-OL 1,2-Benzisoxazol-6-ol,benzo[d]isoxazol-6-ol 1,2-Benzisoxazol-5-ol,4-amino-3-methyl-(9CI) 1,2-Benzisoxazol-4-ol,3-amino-(9CI) 3-(4-CHLORO-PHENYL)-BENZO[D]ISOXAZOL-6-OL 1,2-Benzisoxazol-3-ol,acetate(ester)(9CI) 3-(4-METHOXYPHENYL)-1,2-BENZISOXAZOL-6-OL,3-(4-METHOXY-PHENYL)-BENZO[D]ISOXAZOL-6-OL BENZO[D]ISOXAZOL-3-YL DIPHENYL PHOSPHATE 1,2-Benzisoxazol-5-ol,3-chloro-(9CI) 1,2-Benzisoxazol-4-ol, 6,7-dihydro-3-methyl- (9CI) 1,2-Benzisoxazol-5-ol,6-chloro-(9CI) 1,2-Benzisoxazol-6-ol,5-amino-3-methyl-(9CI) BENZO[D]ISOXAZOL-7-OL 1,2-Benzisoxazol-7-ol,3-chloro-(9CI) 1,2-Benzisoxazol-5-ol, 3-methyl- (9CI)

benzo[d]isoxazol-3(2H)-one

3-Hydroxybenzisoxazole 97%

1,2-benzisoxazol-3(2h)-one

1,2-benzisoxazol-3-ol

1,2-benzisoxazolin-3-one

3-HYDROXY-1,2-BENZISOXAZOLE

3-HYDROXYBENZISOXAZOLE

BUTTPARK 43\57-21

BENZO[D]ISOXAZOL-3-OL

Benzo[d]isoxazol-3-one

1,2-Benzisoxazole-3(2H)-one

Benzo[d]isoxazol-3-ol, 1,2-Benzisoxazol-3-ol

1,2-benzoxazol-3-one

1,2-benzoxazol-3-ol

1,2-benzoxazol-3-ol - [B84997]

21725-69-9

Fused Ring Systems