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N-boc Asp(OH)Ome

Product Name
N-boc Asp(OH)Ome
CAS No.
98045-03-5
Chemical Name
N-boc Asp(OH)Ome
Synonyms
Boc-L-Asp-Ome;N-boc Asp(OH)Ome;1-Methyl N-Boc-L-aspartate;(Tert-Butoxy)Carbonyl Asp-OMe;Boc-L-aspartic acid 1-methyl ester;N-Boc-L-aspartic Acid 1-Methyl Ester;N-Boc-L-aspartic acid 1-Methyl ester, 98%;α-methyl N-(tert-butoxycarbonyl)aspartate;1-Methyl N-(tert-Butoxycarbonyl)-L-aspartate;N-tert-Butoxycarbonyla spartic acid a-methylester
CBNumber
CB71096083
Molecular Formula
C10H17NO6
Formula Weight
247.25
MOL File
98045-03-5.mol
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N-boc Asp(OH)Ome Property

Melting point:
79-81℃
Boiling point:
407.1±40.0 °C(Predicted)
Density 
1.209
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
4.09±0.19(Predicted)
form 
Solid
color 
White to Almost white
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Safety

HS Code 
2924.19.8000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2970
Product name
1-Methyl N-(tert-Butoxycarbonyl)-L-aspartate
Purity
>97.0%(HPLC)(T)
Packaging
5g
Price
$57
Updated
2025/07/31
TRC
Product number
B657183
Product name
Boc-Asp-OMe
Packaging
50mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB72153
Product name
Boc-Asp-OMe
Packaging
25g
Price
$68
Updated
2021/12/16
Oakwood
Product number
M06171
Product name
Boc-Asp-Ome
Packaging
25g
Price
$79
Updated
2021/12/16
Chem-Impex
Product number
24636
Product name
Boc-Asp-OMe,99%(HPLC)
Purity
99%(HPLC)
Packaging
25G
Price
$84
Updated
2021/12/16
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N-boc Asp(OH)Ome Chemical Properties,Usage,Production

Uses

N-Boc-L-aspartic acid 1-methyl ester is used as an intermediate in the preparation of modified alfa-amino acids and 5-cis-alkylprolines.

Synthesis

80963-12-8

98045-03-5

Boc-L-aspartyl (OBn)(OMe)14 (5.88 g, 17.43 mmol) was dissolved in methanol (20 mL) in a 50 mL round-bottomed flask and 10% palladium carbon catalyst was added under nitrogen protection. The reaction system was replaced three times with nitrogen and then three times with hydrogen. Subsequently, the reaction mixture was stirred under hydrogen atmosphere and atmospheric pressure for 6 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford the target product (S)-3-((tert-butoxycarbonyl)amino)-4-methoxy-4-oxobutanoic acid (Compound 15) in the form of a colorless gel (4.1 g, 95% yield). The specific optical rotation [α]21D of the product was 34 (c 0.1, CHCl3).1H NMR (CDCl3, 400 MHz) δ: 1.43 (s, 9H), 2.83-2.86 (d, 1H, J = 16.92 Hz), 3.01-3.05 (d, 1H, J = 16.68 Hz), 3.74 (s, 3H), 4.57 (s , 1H), 5.55-5.57 (d, 1H, J = 8.12 Hz), 10.45 (s, 1H).13C NMR (CDCl3, 100 MHz) δ: 28.3, 36.6, 49.7, 52.8, 80.5, 155.5, 171.5, 176.0. IR (KBr) ν: 3366, 2980, 1719 , 1506, 1440, 1395, 1368, 1222, 1165, 1060, 1008, 864, 764, 587 cm-1.

References

[1] Organic and Biomolecular Chemistry, 2007, vol. 5, # 9, p. 1459 - 1465
[2] Tetrahedron Letters, 2014, vol. 55, # 14, p. 2274 - 2276
[3] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 1, p. 15 - 20
[4] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 2, p. 586 - 590
[5] Carbohydrate Research, 2013, vol. 382, p. 36 - 42

N-boc Asp(OH)Ome Preparation Products And Raw materials

Raw materials

Preparation Products

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N-boc Asp(OH)Ome Suppliers

Americas 1 China 84 Europe 1 India 1 Japan 3 United Kingdom 1 United States 7 Global 98
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
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View Lastest Price from N-boc Asp(OH)Ome manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Boc-L-Asp-Ome 98045-03-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2023-09-24
Career Henan Chemical Co
Product
N-boc Asp(OH)Ome 98045-03-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-03

98045-03-5, N-boc Asp(OH)OmeRelated Search:

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  • N-Boc-L-aspartic acid 1-Methyl ester, 98%
  • N-boc Asp(OH)Ome
  • N-[(1,1-Dimethylethoxy)carbonyl]-L-aspartic acid alpha-methyl ester
  • N-tert-Butoxycarbonyl-L-aspartic acid 1-methyl ester
  • Boc-L-aspartic acid 1-methyl ester
  • 1-Methyl N-(tert-Butoxycarbonyl)-L-aspartate
  • (Tert-Butoxy)Carbonyl Asp-OMe
  • N-tert-Butoxycarbonyla spartic acid a-methylester
  • α-methyl N-(tert-butoxycarbonyl)aspartate
  • (3S)-3-{[(tert-butoxy)carbonyl]amino}-4-methoxy-4-oxobutanoic acid
  • (S)-3-((tert-Butoxycarbonyl)amino)-4-methoxy-4-oxobutanoicacid
  • L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-methyl ester
  • 1-Methyl N-Boc-L-aspartate
  • Boc-L-Asp-Ome
  • N-tert-Butoxycarbonylaspartic acid α-methyl ester
  • N-Boc-L-aspartic Acid 1-Methyl Ester
  • 98045-03-5