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METHYL 2-AMINO-3-CARBOXYBENZOATE

Product Name
METHYL 2-AMINO-3-CARBOXYBENZOATE
CAS No.
253120-47-7
Chemical Name
METHYL 2-AMINO-3-CARBOXYBENZOATE
Synonyms
METHYL 2-AMINO-3-CARBOXYBENZOATE;2-Amino-3-(methoxycarbonyl)benzoi;2- aMino-3- carboxyMethyl benzoate;Methyl 2-amino-3-carboxybenzoate 97%;6-Carboxy-2-(methoxycarbonyl)aniline;2-aMino-3-(Methoxycabonyl)benzoic acid;3-(Methoxycarbonyl)-2-aMinobenzoic acid;2-Amino-3-(methoxycarbonyl)benzoic acid;2-AMINO-ISOPHTHALIC ACID MONOMETHYL ESTER;1-Methyl 2-amino-1,3-benzenedicarboxylate
CBNumber
CB7112924
Molecular Formula
C9H9NO4
Formula Weight
195.17
MOL File
253120-47-7.mol
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METHYL 2-AMINO-3-CARBOXYBENZOATE Property

Melting point:
160 °C
Boiling point:
370.4±32.0 °C(Predicted)
Density 
1.373±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
4.57±0.10(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C9H9NO4/c1-14-9(13)6-4-2-3-5(7(6)10)8(11)12/h2-4H,10H2,1H3,(H,11,12)
InChIKey
UXQCFHRNRAGKOY-UHFFFAOYSA-N
SMILES
C1(C(OC)=O)=CC=CC(C(O)=O)=C1N
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22
Hazard Note 
Irritant
HS Code 
2922500090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A898868
Product name
2-Amino-3-(methoxycarbonyl)benzoicAcid
Packaging
100mg
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA142776
Product name
2-Amino-3-(methoxycarbonyl)benzoic acid
Packaging
500mg
Price
$85
Updated
2021/12/16
SynQuest Laboratories
Product number
4658-1-Y4
Product name
2-Amino-3-(methoxycarbonyl)benzoic acid
Purity
97%
Packaging
250mg
Price
$88
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA142776
Product name
2-Amino-3-(methoxycarbonyl)benzoic acid
Packaging
1g
Price
$151
Updated
2021/12/16
Matrix Scientific
Product number
073875
Product name
2-Amino-3-(methoxycarbonyl)benzoic acid
Purity
95+%
Packaging
1g
Price
$195
Updated
2021/12/16
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METHYL 2-AMINO-3-CARBOXYBENZOATE Chemical Properties,Usage,Production

Synthesis

103030-10-0

253120-47-7

Step 1: Synthesis of 2-amino-3-(methoxycarbonyl)benzoic acid Methyl 2,3-dioxo dihydroindole-7-carboxylate (1 eq.) was dissolved in methanol (0.4 M) and hydrogen chloride gas was passed into the solution at 0 °C with continuous stirring of the reaction mixture for 2 hours. After completion of the reaction, the solvent was removed by evaporation and the resulting residue was diluted with chloroform, washed sequentially with saturated aqueous sodium bicarbonate and brine, and the organic phase was dried over anhydrous sodium sulfate and then concentrated to give the crude product (MS (ES+) m/z 206 (M+H)+). The above crude product was dissolved in 10% aqueous hydrogen peroxide solution, prepared as 0.2 M. An equal volume of 2.5% aqueous sodium hydroxide solution was added and the reaction was stirred for 15 min at room temperature. At the end of the reaction, the reaction mixture was acidified with concentrated hydrochloric acid, the precipitate precipitated was collected by filtration and washed with water to obtain monomethyl 2-aminoisophthalate in 88% yield as a white powder. Product characterization data: 1H NMR (400MHz, DMSO-d6, 300K) δ 3.82 (s, 3H), 6.60 (t, 1H, J=7.4Hz), 8.04 (m, 3H), 12.94 (bs, 1H); MS (ES+) m/z 196 (M+H)+.

References

[1] Synthetic Communications, 1999, vol. 29, # 23, p. 4223 - 4233
[2] Patent: WO2007/28789, 2007, A1. Location in patent: Page/Page column 31

METHYL 2-AMINO-3-CARBOXYBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 2-AMINO-3-CARBOXYBENZOATE Suppliers

Belgium 1 China 90 Europe 1 France 1 Germany 3 India 1 United Kingdom 8 United States 13 Global 118
Interchim S.A.
Tel
--
Fax
--
Email
interchim@interchim.com
Country
France
ProdList
6302
Advantage
76
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View Lastest Price from METHYL 2-AMINO-3-CARBOXYBENZOATE manufacturers

Career Henan Chemical Co
Product
METHYL 2-AMINO-3-CARBOXYBENZOATE 253120-47-7
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-01-08

253120-47-7, METHYL 2-AMINO-3-CARBOXYBENZOATERelated Search:

Isophthalic acid METHYL 2-AMINO-3-CARBOXYBENZOATE AKOS 243-18 METHYL 3-(METHOXYCARBONYL)-2-((PHENYLCYCLOPENTYL)CARBONYLAMINO)BENZOATE 2-NITRO-ISOPHTHALIC ACID MONOMETHYL ESTER 3-ISATOIC ANHYDRIDE CARBOXYLIC ACID METHYL ESTER 1,4-Dihydro-2,4-dioxo-2H-3,1-benzoxazine-8-carboxylic acid

  • METHYL 2-AMINO-3-CARBOXYBENZOATE
  • 2-AMINO-ISOPHTHALIC ACID MONOMETHYL ESTER
  • Methyl 2-amino-3-carboxybenzoate 97%
  • 1,3-Benzenedicarboxylicacid,2-amino-,monomethylester(9CI)
  • 2-Amino-3-(methoxycarbonyl)benzoic acid
  • 2- aMino-3- carboxyMethyl benzoate
  • 2-aMino-3-(Methoxycabonyl)benzoic acid
  • 2-Amino-3-(methoxycarbonyl)benzoic acid 97%
  • 2-Carboxy-6-(methoxycarbonyl)aniline, Methyl 2-amino-3-carboxybenzoate, 1-Methyl 2-aminoisophthalate
  • 1,3-Benzenedicarboxylic acid, 2-amino-, 1-methyl ester
  • 6-Carboxy-2-(methoxycarbonyl)aniline
  • 2-Amino-3-(methoxycarbonyl)benzoi
  • 3-(Methoxycarbonyl)-2-aMinobenzoic acid
  • METHYL 2-AMINO-3-CARBOXYBENZOATE USP/EP/BP
  • 1-Methyl 2-amino-1,3-benzenedicarboxylate
  • 253120-47-7
  • Esters
  • Phenyls & Phenyl-Het
  • AMINOACID