ChemicalBook > CAS DataBase List > Dexelvucitabine

Dexelvucitabine

Product Name
Dexelvucitabine
CAS No.
134379-77-4
Chemical Name
Dexelvucitabine
Synonyms
RVT;YZ 817;D-D-4FC;DPC-817;Reverset;RA 131423;INCB 8721;beta-D-D-4FC;Dexelvucitabine;Dexelvucitabine, 10 mM in DMSO
CBNumber
CB71178464
Molecular Formula
C9H10FN3O3
Formula Weight
227.19
MOL File
134379-77-4.mol
More
Less

Dexelvucitabine Property

Boiling point:
394.9±52.0 °C(Predicted)
Density 
1.66±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:0.0(Max Conc. mg/mL);0.0(Max Conc. mM)
form 
Solid
pka
14.28±0.10(Predicted)
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
NF58422
Product name
5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine
Packaging
25mg
Price
$225
Updated
2021/12/16
Biosynth Carbosynth
Product number
NF58422
Product name
5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine
Packaging
50mg
Price
$363
Updated
2021/12/16
Biosynth Carbosynth
Product number
NF58422
Product name
5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine
Packaging
100mg
Price
$580
Updated
2021/12/16
Biosynth Carbosynth
Product number
NF58422
Product name
5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine
Packaging
250mg
Price
$880
Updated
2021/12/16
AK Scientific
Product number
3713CA
Product name
Dexelvucitabine
Packaging
250mg
Price
$1238
Updated
2021/12/16
More
Less

Dexelvucitabine Chemical Properties,Usage,Production

Uses

Treatment of HIV-1 and HIV-2 infection.

Uses

Dexelvucitabine is a nucleoside reverse transcriptase inhibitor (NRTI) which had the potential to inhibit HIV-1 replication. The drug was discontinued due to evidence that it causes damage to the pancreas.

brand name

Reverset (Incyte).

in vivo

Dexelvucitabine (Reverset; d-d4FC; 33.3 mg/kg by i.v. or p.o.) has distribution and elimination half-lives (t1/2α?and?t1/2β, respectively) of 0.7 and 3.6 h in monkeys, respectively. The Cmax ranges from 21.1 to 47.5 μM[2].
Dexelvucitabine has a favorable pharmacokinetic profile with a long half-life (4.71 and 10.75 h after administration by the intravenous [i.v.] and oral [p.o.] routes, respectively)?in woodchucks[2].

IC 50

HIV-1

Dexelvucitabine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Dexelvucitabine Suppliers

China 22 South Korea 1 United Kingdom 1 United States 5 Global 29
Shanghai Fuhe Chemistry Technology Co., Ltd.
Tel
0086-21-67651709
Fax
0086-21-67651705
Email
cfx759@hotmail.com
Country
China
ProdList
410
Advantage
57
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Zhengzhou GranLen pharmaceutical Technology Co., Ltd.
Tel
0371-85513397
Email
info@granlen.com
Country
China
ProdList
497
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Maanshan geneyan biotech Co.,LTD
Tel
18913822354
Email
market@geneyan-bio.com
Country
China
ProdList
300
Advantage
58
NewCan Biotech Limited
Tel
+86-0571-86912261 +8613735419629
Email
sales@newcanbio.com
Country
China
ProdList
9985
Advantage
58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tel
+86-021-61551413 +8618813727289
Email
contact@trustwe.com
Country
China
ProdList
5743
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Shanghai Saikerui Biotechnology Co. , Ltd.
Tel
021-58000709 15900491054
Email
info@scrbio.com
Country
China
ProdList
9881
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11973
Advantage
58
Shanghai Beiwanta Biotechnology Co., Ltd.
Tel
021-67187366 19901745723
Email
info@bwtlab.com
Country
China
ProdList
9651
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12000
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9835
Advantage
58
Shanghai Weiyite Biotechnology Co., Ltd
Tel
15317051735
Email
zhaojing@wytsci.com
Country
China
ProdList
9980
Advantage
58
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6710
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Shanghai Scibiotron Pharmaceutical Co., Ltd
Tel
+86-16621589600
Email
contact@scibiotron.com
Country
China
ProdList
5535
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
+undefined18143011203
Email
info@chemextension.com
Country
China
ProdList
42056
Advantage
58
Guangzhou Baide Biotechnology Co., Ltd.
Tel
18925065404
Country
CHINA
ProdList
168
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58
Proteintech China
Tel
--
Fax
--
Email
Proteintech-CN@ptglab.com
Country
CHINA
ProdList
6290
Advantage
58
Lanospharma Laboratories Co.,Ltd
Tel
--
Fax
--
Email
sales@lanospharma.com
Country
China
ProdList
6329
Advantage
56

134379-77-4, DexelvucitabineRelated Search:

5-Fluorocytidine Dexelvucitabine 2',3'-DIDEHYDRO-2',3'-DIDEOXY-5-FLUORO-BETA-D-CYTIDINE, [6-3H]-

  • Dexelvucitabine
  • 2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine
  • 4-AMINO-5-FLUORO-1-[(2R,5S)-5-(HYDROXYMETHYL)-2,5-DIHYDROFURAN-2-YL]PYRIMIDIN-2(1H)-ONE
  • Cytidine,2',3'-didehydro-2',3'-dideoxy-5-fluoro-
  • INCB 8721
  • RA 131423
  • Reverset
  • YZ 817
  • 5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine
  • 2’,3’-Dideoxy-2’,3’-didehydro-5-fluoro-cytidine, FddddC, Dexelvucitabine (DFC), Reverset
  • beta-D-D-4FC
  • D-D-4FC
  • DPC-817
  • RVT
  • 5-Fluoro-1-(2’,3’-dideoxy-2’,3’-didehydro-β-D-arabinofuranosyl)-cytosine (Dexelvucitabine)
  • Inhibitor,thymidine,Human immunodeficiency virus,d-d4FC,cytidine,M184V mutation,antiretroviral,inhibit,Reverset,2′-deoxycytidine,viral polymerase,Dexelvucitabine,HIV,resistant viruse,nucleoside reverse transcriptase,HIV-1,Reverse Transcriptase
  • 2',3'-didehydro-2',3'-dideoxy-5-fluoroCytidine
  • Dexelvucitabine, 10 mM in DMSO
  • 134379-77-4