ChemicalBook > CAS DataBase List > Dinalin

Dinalin

Product Name
Dinalin
CAS No.
58338-59-3
Chemical Name
Dinalin
Synonyms
Dinalin;GOE1734;dinaline;PD-104208;Dinaline, Antineoplastic agent;Benzamide, 4-amino-N-(2-aminophenyl)-
CBNumber
CB71178530
Molecular Formula
C13H13N3O
Formula Weight
227.26
MOL File
58338-59-3.mol
More
Less

Dinalin Property

Melting point:
180.5°C
Boiling point:
368.98°C (rough estimate)
Density 
1.1267 (rough estimate)
refractive index 
1.5600 (estimate)
storage temp. 
Store at Room Tem.
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
INB0001967
Product name
4-AMINO-N-(2-AMINOPHENYL)-BENZAMIDE
Purity
95.00%
Packaging
5MG
Price
$504.2
Updated
2021/12/16
Acrotein
Product number
AM-0721
Product name
4-Amino-N-(2-aminophenyl)-benzamide
Purity
97%
Packaging
1g
Price
$275
Updated
2021/12/16
More
Less

Dinalin Chemical Properties,Usage,Production

Uses

Dinaline (GOE 1734; PD 104 208; NSC 328786) is a potent and orally activity anticancer agent. Dinaline shows cytotoxicity and antitumor activity. Dinaline has the potential for the research of colorectal cancer[1].

in vivo

Dinaline (5.9, 7.7, 10 mg/kg; p.o.; 5 days per week for 10 weeks) inhibits tumor growth in rats[1].

Animal Model:140-160 g, male Sprague-Dawley rats[1]
Dosage:5.9, 7.7, 10 mg/kg
Administration:P.o.; 5 days per week for 10 weeks
Result:Showed significant tumor growth inhibition in a dose-dependent manner with the ratio of median tumor volume of (T/C%) values of 0.4, 16 and 10.6 at 10, 7.7 and 5.9 mg/kg respectively.

References

[1] Seelig MH, et al. Efficacy of dinaline and its methyl and acetyl derivatives against colorectal cancer in vivo and in vitro. Eur J Cancer. 1996 Oct;32A(11):1968-76. DOI:10.1016/0959-8049(96)00217-1

Dinalin Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Dinalin Suppliers

Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
Shanghai Rechem science Co., Ltd.
Tel
021-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2991
Advantage
58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19987
Advantage
58
Beijing Biocreative Technology Co., Ltd.
Tel
15522676233
Email
3007606172@qq.com
Country
China
ProdList
1248
Advantage
58
Aikon International Limited
Tel
025-58859352 18921922613
Email
hywu@aikonchem.com
Country
China
ProdList
10709
Advantage
58
Changzhou Qianai Biotechnology Co., Ltd
Tel
051915240519135 13961152745
Email
yudiguimo@126.COM
Country
China
ProdList
10000
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Guangdong Liusheng Trading Co., Ltd.
Tel
13676271149
Country
CHINA
ProdList
183
Advantage
58

58338-59-3, DinalinRelated Search:


  • Dinalin
  • dinaline
  • GOE1734
  • PD-104208
  • Benzamide, 4-amino-N-(2-aminophenyl)-
  • Dinaline, Antineoplastic agent
  • 58338-59-3