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Loprazolam

Product Name
Loprazolam
CAS No.
61197-73-7
Chemical Name
Loprazolam
Synonyms
RU-31158;triazulenone;Loprazolam solution;Loprazolam USP/EP/BP;Loprazolam (1mg/mL in Acetonitrile);(2Z)-6-(2-chlorophenyl)-2-[(4-methylpiperazin-1-yl)methylidene]-8-nitro-4H-imidazo[1,2-a][1,4]benzodiazepin-1-one;6-(2-Chlorophenyl)-2,4-dihydro-2-[(4-methylpiperazin-1-yl)methylene]-8-nitro-1H-imidazo[1,2-a][1,4]benzodiazepin-1-one;(Z)-6-(2-Chlorophenyl)-2,4-dihydro-2-[(4-methyl-1-piperazinyl)methylene]-8-nitro-1H-imidazo[1,2-a][1,4]benzodiazepin-1-one;1H-Imidazo[1,2-a][1,4]benzodiazepin-1-one, 6-(2-chlorophenyl)-2,4-dihydro-2-[(4-methyl-1-piperazinyl)methylene]-8-nitro-, (2Z)-
CBNumber
CB71179067
Molecular Formula
C23H21ClN6O3
Formula Weight
464.9
MOL File
61197-73-7.mol
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Loprazolam Property

Melting point:
214-215°
Boiling point:
597.5±60.0 °C(Predicted)
Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonictaed)
form 
Solid
pka
6.79±0.42(Predicted)
color 
Yellow to Dark Yellow
Stability:
Light Sensitive
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Safety

RIDADR 
3249
HazardClass 
6.1(b)
PackingGroup 
III
Toxicity
LD50 in mice: >1000 mg/kg orally (Agar)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L-049
Product name
Loprazolam solution
Purity
1?mg/mL (Acetonitrile:DMSO (90:10) (v/v)), certified reference material, ampule of 1?mL, Cerilliant?
Packaging
1mL
Price
$369
Updated
2024/03/01
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Loprazolam Chemical Properties,Usage,Production

Uses

Sedative, hypnotic. Controlled substance (depressant).

Definition

ChEBI: Loprazolam is an imidazobenzodiazepine.

Loprazolam Preparation Products And Raw materials

Raw materials

Preparation Products

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Loprazolam Suppliers

61197-73-7, LoprazolamRelated Search:


  • 6-(2-Chlorophenyl)-2,4-dihydro-2-[(4-methylpiperazin-1-yl)methylene]-8-nitro-1H-imidazo[1,2-a][1,4]benzodiazepin-1-one
  • RU-31158
  • triazulenone
  • (Z)-6-(2-Chlorophenyl)-2,4-dihydro-2-[(4-methyl-1-piperazinyl)methylene]-8-nitro-1H-imidazo[1,2-a][1,4]benzodiazepin-1-one
  • (2Z)-6-(2-chlorophenyl)-2-[(4-methylpiperazin-1-yl)methylidene]-8-nitro-4H-imidazo[1,2-a][1,4]benzodiazepin-1-one
  • Loprazolam solution
  • Loprazolam (1mg/mL in Acetonitrile)
  • 1H-Imidazo[1,2-a][1,4]benzodiazepin-1-one, 6-(2-chlorophenyl)-2,4-dihydro-2-[(4-methyl-1-piperazinyl)methylene]-8-nitro-, (2Z)-
  • Loprazolam USP/EP/BP
  • 61197-73-7
  • C23H21CLN6O3
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals