ChemicalBook > CAS DataBase List > Metyrapone
Metyrapone
- Product Name
- Metyrapone
- CAS No.
- 908-35-0
- Chemical Name
- Metyrapone
- Synonyms
- Metopirone tartrate;METYRAPONEDITARTRATE
- CBNumber
- CB71179188
- Molecular Formula
- C22H26N2O13
- Formula Weight
- 526.44744
- MOL File
- 908-35-0.mol
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Metyrapone Chemical Properties,Usage,Production
Uses
Diagnostic aid (pituitary function determination).
brand name
Metopirone Ditartrate (Ciba-Geigy).
in vivo
Metyrapone (25 or 50 mg/kg; SC, single dosage) decreases the stress-induced increase in plasma corticosterone levels, significantly impairs acquisition performance at high dosage, and increases open arm activity at low dosage[1].
| Animal Model: | Male Sprague-Dawley rats (n=179; 270-300g)[1] |
| Dosage: | 25 or 50 mg/kg (in a volume of 2.0 ml/kg) |
| Administration: | SC, single dosage |
| Result: | Dose-dependently decreased the stress-induced increase in plasma corticosterone levels in the water maze test; the high level dose significantly impaired acquisition performance in the water maze and decreased fear-induced immobility; the lower dose increased open arm activity. |
Metyrapone Preparation Products And Raw materials
Raw materials
Preparation Products
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Metyrapone Suppliers
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- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
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- Advantage
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- marketing@targetmol.cn
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- China
- ProdList
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