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Safrazine

Product Name
Safrazine
CAS No.
33419-68-0
Chemical Name
Safrazine
Synonyms
Safrasine;Safrazine;Saphrazine;4-(1,3-benzodioxol-5-yl)butan-2-ylhydrazine;1-[3-(1,3-Benzodioxol-5-yl)-1-methylpropyl]hydrazine
CBNumber
CB71179698
Molecular Formula
C11H16N2O2
Formula Weight
208.25694
MOL File
33419-68-0.mol
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Safrazine Property

Boiling point:
347.46°C (rough estimate)
Density 
1.1123 (rough estimate)
refractive index 
1.5000 (estimate)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0012453
Product name
SAFRAZINE
Purity
95.00%
Packaging
5MG
Price
$505.34
Updated
2021/12/16
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Safrazine Chemical Properties,Usage,Production

Uses

Safrazine is an irreversible, non-specific and orally active monoamine oxidase (MAO) inhibitor. Safrazine can be used for the research of depression[1].

in vivo

Safrazine (oral; 3, 10, 30 mg/kg) causes the increases contents of monoamine lasted for at least 24 h[1].
Safrazine strongly inhibits both 5-HT and PEA deaminations, but shows no selectivity toward the substrate used[1].

Animal Model:Male ddY mice[1]
Dosage:3, 10, 30 mg/kg
Administration:Oral
Result:Inhibited significantly both 5-HT and PEA deaminations at only 3 mg/kg by 77% and 71%, respectively.
Completely reduced both deaminations at 10 and 30 mg/kg and not observed specificity toward substrates.

References

[1] T Yokoyama, et al. Comparative studies of the effects of RS-8359 and safrazine on monoamine oxidase in-vitro and in-vivo in mouse brain. J Pharm Pharmacol. 1989 Jan;41(1):32-6. DOI:10.1111/j.2042-7158.1989.tb06324.x

Safrazine Preparation Products And Raw materials

Raw materials

Preparation Products

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Safrazine Suppliers

China 2 South Korea 1 United States 2 Global 5
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29357
Advantage
58
TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19961
Advantage
58

33419-68-0, SafrazineRelated Search:


  • Safrazine
  • 1-[3-(1,3-Benzodioxol-5-yl)-1-methylpropyl]hydrazine
  • Safrasine
  • Saphrazine
  • 4-(1,3-benzodioxol-5-yl)butan-2-ylhydrazine
  • 33419-68-0
  • 771320-77-9