ChemicalBook > CAS DataBase List > 2-IODO-6-METHOXYPYRAZINE

2-IODO-6-METHOXYPYRAZINE

Product Name
2-IODO-6-METHOXYPYRAZINE
CAS No.
58139-03-0
Chemical Name
2-IODO-6-METHOXYPYRAZINE
Synonyms
2-IODO-6-METHOXYPYRAZINE;Pyrazine, 2-iodo-6-methoxy-;2-Iodo-6-methoxypyrazine 95%
CBNumber
CB71215909
Molecular Formula
C5H5IN2O
Formula Weight
236.01
MOL File
58139-03-0.mol
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2-IODO-6-METHOXYPYRAZINE Property

Melting point:
36.6-38.1°C
Flash point:
>110℃
form 
solid
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Safety

Hazard Codes 
Xn
Risk Statements 
10-22-37/38-41
Safety Statements 
16-26-37
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
759228
Product name
2-Iodo-6-methoxypyrazine
Purity
95%
Packaging
1g
Price
$89.2
Updated
2023/06/20
TRC
Product number
I737100
Product name
2-Iodo-6-methoxypyrazine
Packaging
50mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0070613
Product name
2-IODO-6-METHOXYPYRAZINE
Purity
95.00%
Packaging
1G
Price
$764.61
Updated
2021/12/16
AK Scientific
Product number
V6755
Product name
2-Iodo-6-methoxypyrazine
Packaging
1g
Price
$114
Updated
2021/12/16
Matrix Scientific
Product number
069584
Product name
2-Iodo-6-methoxypyrazine
Purity
98%
Packaging
1g
Price
$171
Updated
2021/12/16
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2-IODO-6-METHOXYPYRAZINE Chemical Properties,Usage,Production

Synthesis

58138-79-7

58139-03-0

Phase 2: Preparation of 2-iodo-6-methoxypyrazine 2,6-Diiodopyrazine (5.0 g, 15 mmol) was added to a pre-prepared methanolic solution of sodium methanolate (prepared by reacting sodium metal (0.35 g, 15 mmol) with methanol (40 mL)). The reaction mixture was heated to reflux temperature and maintained for 1 hour. After completion of the reaction, it was cooled to room temperature and the reaction solution was diluted with water (200 mL) and subsequently extracted with diethyl ether (3 × 100 mL). The organic phases were combined, washed with water, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to afford 2-iodo-6-methoxypyrazine as a white solid (3.5 g, 100% yield). Melting point: 35.7-37.2 °C. NMR hydrogen spectrum (90 MHz, CDCl3): δ 8.40 (1H, single peak), 8.16 (1H, single peak), 3.98 (3H, single peak). Mass spectrum (m/z): 236 (M+), 127, 109 (100%).

References

[1] Patent: US4975112, 1990, A
[2] Patent: US5260293, 1993, A

2-IODO-6-METHOXYPYRAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-IODO-6-METHOXYPYRAZINE Suppliers

Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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sales@chemreagents.com
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Sigma-Aldrich
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