ChemicalBook > CAS DataBase List > 4-BROMO-2-METHYL-2H-INDAZOLE

4-BROMO-2-METHYL-2H-INDAZOLE

Product Name
4-BROMO-2-METHYL-2H-INDAZOLE
CAS No.
590417-93-9
Chemical Name
4-BROMO-2-METHYL-2H-INDAZOLE
Synonyms
2-Methyl-4-bromoindazole;4-Bromo-2-methylindazole;-BROMO-2-METHYL-2H-INDAZOLE;4-BROMO-2-METHYL-2H-INDAZOLE;4-Bromo-2-methyl-1H-indazole;2H-Indazole, 4-bromo-2-methyl-;4-Bromo-2-methyl-2H-indazole
CBNumber
CB71215954
Molecular Formula
C8H7BrN2
Formula Weight
211.06
MOL File
590417-93-9.mol
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4-BROMO-2-METHYL-2H-INDAZOLE Property

Boiling point:
322.7±15.0 °C(Predicted)
Density 
1.60±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
solid
pka
-0.02±0.30(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C8H7BrN2/c1-11-5-6-7(9)3-2-4-8(6)10-11/h2-5H,1H3
InChIKey
OFOZLGCQBJDWRJ-UHFFFAOYSA-N
SMILES
N1=C2C(C(Br)=CC=C2)=CN1C
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00128
Product name
4-Bromo-2-methyl-2H-indazole
Purity
Aldrich
Packaging
1g
Price
$259
Updated
2025/07/31
TRC
Product number
B697248
Product name
4-Bromo-2-methyl-2H-indazole
Packaging
250mg
Price
$45
Updated
2021/12/16
TRC
Product number
B697248
Product name
4-Bromo-2-methyl-2H-indazole
Packaging
500mg
Price
$70
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-9-X4
Product name
4-Bromo-2-methyl-2H-indazole
Packaging
250mg
Price
$64
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-9-X4
Product name
4-Bromo-2-methyl-2H-indazole
Packaging
1g
Price
$111
Updated
2021/12/16
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4-BROMO-2-METHYL-2H-INDAZOLE Chemical Properties,Usage,Production

Uses

4-Bromo-2-methyl-2H-indazole is mainly used as a chemical reagent and organic synthesis intermediate in the field of scientific research.

Synthesis

420-37-1

186407-74-9

590417-93-9

The general procedure for the synthesis of 4-bromo-2-methyl-2H-indazole from trimethoxonium tetrafluoroborate and 4-bromo-1H-indazole was as follows: with reference to Example 33, 4-bromo-1H-indazole (2.24 g, 11.4 mmol) was dissolved in ethyl acetate (110 mL) and trimethoxonium tetrafluoroborate (2.19 g, 14.8 mmol) was added. The reaction mixture was stirred at room temperature for 3 hours. After completion of the reaction, the reaction solution was diluted with ethyl acetate, washed sequentially with aqueous sodium bicarbonate and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure and the resulting residue was purified by silica gel column chromatography (eluent: ethyl acetate/hexane=10/90→40/60) to afford 4-bromo-2-methyl-2H-indazole (2.29 g, 95% yield). The product was characterized by 1H-NMR (CDCl3): δ 4.23 (3H, s), 7.13 (1H, dd, J=8.5,7.2 Hz), 7.23 (1H, dd, J=7.2,0.8 Hz), 7.60-7.44 (1H, m), 7.91 (1H, m). The mass spectrum (ESI+) showed the molecular ion peak m/z 211 (M+H).

References

[1] Patent: EP2141150, 2010, A1. Location in patent: Page/Page column 63-64

4-BROMO-2-METHYL-2H-INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BROMO-2-METHYL-2H-INDAZOLE Suppliers

Suzhou Xingbei Pharmaceutical Technology Co., Ltd
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View Lastest Price from 4-BROMO-2-METHYL-2H-INDAZOLE manufacturers

Career Henan Chemical Co
Product
4-BROMO-2-METHYL-2H-INDAZOLE 590417-93-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2020-01-02

590417-93-9, 4-BROMO-2-METHYL-2H-INDAZOLERelated Search:


  • 4-BROMO-2-METHYL-2H-INDAZOLE
  • 2-Methyl-4-bromoindazole
  • -BROMO-2-METHYL-2H-INDAZOLE
  • 4-Bromo-2-methylindazole
  • 2H-Indazole, 4-bromo-2-methyl-
  • 4-Bromo-2-methyl-1H-indazole
  • 4-Bromo-2-methyl-2<i>H</i>-indazole
  • 590417-93-9
  • Indazole
  • Organohalides