(3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol

Product Name: (3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol
CAS No.: 64284-64-6
Chemical Name: (3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol
Synonyms: FF-MAS;4,4-Dimethylcholesta-8,14,24-trienol;Follicular Fluid Meiosis-activating Sterol;4,4-DiMethyl-5α-cholesta-8,14,24-trien-3β-ol;"(3β,5a)-4,4-Dimethylcholesta-8,14,24-trien-3-ol";FF-MAS(Follicular fluid meiosis-activating sterol);4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol;Cholesta-8,14,24-trien-3-ol, 4,4-dimethyl-, (3β,5α)-;(3β,5α)-4,4-DiMethylcholesta-8,14,24-trien-3-ol (Contain up to 15% 25 isoMer);(3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol (Contain up to 15% ?25 isomer)
CBNumber: CB71235536
Molecular Formula: C29H46O
Formula Weight: 410.67
MOL File: 64284-64-6.mol

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(3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol Property

Melting point:: 120 - 122°C
Boiling point:: 512.6±49.0 °C(Predicted)
Density: 1.00±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 15.15±0.70(Predicted)
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26093
Product name: FF-MAS
Purity: ≥90%
Packaging: 1mg
Price: $887
Updated: 2024/03/01

Cayman Chemical

Product number: 26093
Product name: FF-MAS
Purity: ≥90%
Packaging: 500μg
Price: $325
Updated: 2021/12/16

TRC

Product number: D471725
Product name: (3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol(Containupto15%∆25isomer)
Packaging: 5mg
Price: $6295
Updated: 2021/12/16

AK Scientific

Product number: 2894CC
Product name: 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
Packaging: 1mg
Price: $934
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 40050
Product name: (3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol
Packaging: 0.5mg
Price: $1150
Updated: 2021/12/16

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(3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol Chemical Properties,Usage,Production

Uses

(3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol is a follicular fluid meiosis-activating sterol (FF-MAS); a factor present in the pre-ovulatory follicle during the time of oocyte maturation. (3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol has been shown to protect young oocytes from precocious chromatid separation as well as protecting aged oocytes from predivision during maturation.

Definition

ChEBI: 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol is a 3beta-sterol and a Delta(14) steroid. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It derives from a hydride of a 5alpha-cholestane.

Biological Activity

14-demethyl-14-dehydrolanosterol (FF-MAS) was first identified in follicular fluid of women and plays a key role in oocyte nuclear maturation. The levels of FF-MAS may be regulated by cytochrome P450 family 27 subfamily A member 1. Supplementation of FF-MAS to oocytes promotes meiotic maturation favoring preimplantation. However, FF-MAS has low solubility and is metabolized to cholesterol rapidly.

(3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol Preparation Products And Raw materials

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(3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol Suppliers

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64284-64-6, (3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-olRelated Search:

(3R,5S,10S,13S,17S)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol

4,4-Dimethylcholesta-8,14,24-trienol

(3β,5α)-4,4-DiMethylcholesta-8,14,24-trien-3-ol (Contain up to 15% 25 isoMer)

4,4-DiMethyl-5α-cholesta-8,14,24-trien-3β-ol

FF-MAS

Follicular Fluid Meiosis-activating Sterol

4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol

Cholesta-8,14,24-trien-3-ol, 4,4-dimethyl-, (3β,5α)-

(3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol (Contain up to 15% ?25 isomer)

"(3β,5a)-4,4-Dimethylcholesta-8,14,24-trien-3-ol"

FF-MAS(Follicular fluid meiosis-activating sterol)

64284-64-6

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Steroids