ChemicalBook > CAS DataBase List > 2-hydroxy-4-oxo-pentanedioic acid
2-hydroxy-4-oxo-pentanedioic acid
- Product Name
- 2-hydroxy-4-oxo-pentanedioic acid
- CAS No.
- 1187-99-1
- Chemical Name
- 2-hydroxy-4-oxo-pentanedioic acid
- Synonyms
- DL-KHG Li;2-keto-4-hydroxyglutarate;DL-4-Hydroxy-2-ketoglutarate;4-Hydroxy-2-oxoglutaric acid;2-hydroxy-4-oxo-pentanedioic acid;Pentanedioic acid, 2-hydroxy-4-oxo-;4-Hydroxy-2-oxoglutaric acid lithium salt;DL-4-Hydroxy-2-ketoglutarate disodium salt;DL-4-Hydroxy-2-ketoglutarate DilithiuM Salt;DL-4-Hydroxy-2-ketoglutaric acid lithium salt
- CBNumber
- CB71235556
- Molecular Formula
- C5H6O6
- Formula Weight
- 162.1
- MOL File
- 1187-99-1.mol
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2-hydroxy-4-oxo-pentanedioic acid Property
- Melting point:
- >250°C (dec.)
- Boiling point:
- 425.6±35.0 °C(Predicted)
- Density
- 1.700±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Water
- pka
- 2.34±0.54(Predicted)
- form
- Solid
- color
- Off-White
- BRN
- 1780096
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 96599
- Product name
- DL-4-Hydroxy-2-ketoglutaric acid lithium salt
- Purity
- ≥90.0% (TLC)
- Packaging
- 50mg
- Price
- $417
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 96599
- Product name
- DL-4-Hydroxy-2-ketoglutaric acid lithium salt
- Purity
- ≥90.0% (TLC)
- Packaging
- 10mg
- Price
- $111
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- 61076
- Product name
- DL-4-Hydroxy-2-ketoglutaric acid lithium salt
- Purity
- analytical standard
- Packaging
- 10mg
- Price
- $105
- Updated
- 2022/05/15
Sigma-Aldrich
- Product number
- 61076
- Product name
- DL-4-Hydroxy-2-ketoglutaric acid lithium salt
- Purity
- analytical standard
- Packaging
- 50mg
- Price
- $316
- Updated
- 2022/05/15
Usbiological
- Product number
- 279270
- Product name
- DL-4-Hydroxy-2-ketoglutarate dilithium salt
- Packaging
- 5mg
- Price
- $355
- Updated
- 2021/12/16
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2-hydroxy-4-oxo-pentanedioic acid Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Uses
A 4-substituted analog of Glutamic acid. This compound is a good enzyme substrate for GOT (glutamic oxalacetic aminotransferase).
Definition
ChEBI: An oxo dicarboxylic acid comprising glutaric acid having oxo- and hydroxy substituents at the 2- and 4-positions respectively.
Biological Activity
DL-4-Hydroxy-2-ketoglutaric acid (DL-KHG) is an enzyme substrate for GOT (glutamic oxalacetic aminotransferase) and 2-Keto-4-hydroxyglutarate aldolase, which catalyzes the reversible cleavage of 2-keto-4-hydroxyglutarate yielding pyruvate plus glyoxylate; DL-KHG has been used in mass spectrometry for the rapid analysis of negatively charged water-soluble cellular metabolites.
2-hydroxy-4-oxo-pentanedioic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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2-hydroxy-4-oxo-pentanedioic acid Suppliers
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