6-Benzothiazolol,2-(methylthio)-(9CI)
- Product Name
- 6-Benzothiazolol,2-(methylthio)-(9CI)
- CAS No.
- 74537-49-8
- Chemical Name
- 6-Benzothiazolol,2-(methylthio)-(9CI)
- Synonyms
- 2-Methylthiobenzothiazol-6-ol;6-Benzothiazolol, 2-(methylthio)-;2-(Methylthio)benzo[d]thiazol-6-ol;6-Benzothiazolol,2-(methylthio)-(9CI);2-(methylsulfanyl)-1,3-benzothiazol-6-ol
- CBNumber
- CB71277239
- Molecular Formula
- C8H7NOS2
- Formula Weight
- 197.28
- MOL File
- 74537-49-8.mol
6-Benzothiazolol,2-(methylthio)-(9CI) Property
- Melting point:
- 131-132 °C
- Boiling point:
- 375.3±34.0 °C(Predicted)
- Density
- 1.46±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 8.43±0.40(Predicted)
- InChI
- InChI=1S/C8H7NOS2/c1-11-8-9-6-3-2-5(10)4-7(6)12-8/h2-4,10H,1H3
- InChIKey
- IAQHORMPRYVLJX-UHFFFAOYSA-N
- SMILES
- S1C2=CC(O)=CC=C2N=C1SC
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 6710DF
- Product name
- 2-(Methylthio)benzo[d]thiazol-6-ol
- Packaging
- 1g
- Price
- $199
- Updated
- 2021/12/16
- Product number
- 132020
- Product name
- 2-(Methylthio)benzo[d]thiazol-6-ol
- Purity
- 95%
- Packaging
- 500mg
- Price
- $396
- Updated
- 2021/12/16
- Product number
- 132020
- Product name
- 2-(Methylthio)benzo[d]thiazol-6-ol
- Purity
- 95%
- Packaging
- 1g
- Price
- $630
- Updated
- 2021/12/16
- Product number
- 8H70-1-1S
- Product name
- 2-(Methylthio)benzo[d]thiazol-6-ol
- Packaging
- 500mg
- Price
- $647
- Updated
- 2021/12/16
- Product number
- CHM0167595
- Product name
- 2-(METHYLTHIO)BENZO[D]THIAZOL-6-OL
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1443.75
- Updated
- 2021/12/16
6-Benzothiazolol,2-(methylthio)-(9CI) Chemical Properties,Usage,Production
Synthesis
74537-63-6
74-88-4
74537-49-8
Step 2. Preparation of 2-(methylmercapto)benzo[d]thiazol-6-ol: 2-mercaptobenzo[d]thiazol-6-ol (3.80 g, 20.76 mmol, 1.0 eq.) obtained from Step 1 was dissolved in dichloromethane (40 mL, 0.5 M) and cooled to 0 °C in an ice bath. Under stirring, triethylamine (7.29 mL, 51.91 mmol, 2.5 eq.) and iodomethane (1.93 mL, 31.14 mmol, 1.5 eq.) were added sequentially. The reaction temperature was maintained between 0 °C and -10 °C with continuous stirring for 3 hours. Upon completion of the reaction, the solvent was removed by rotary evaporator under reduced pressure. Water (~200 mL) was added to the residue and the aqueous layer was subsequently extracted with ethyl acetate (3 x 150 mL). The organic layers were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 2-(methylmercapto)benzo[d]thiazol-6-ol (3.76 g, 92% yield) in light green powder form.
References
[1] Patent: US2008/45528, 2008, A1. Location in patent: Page/Page column 47
[2] Australian Journal of Chemistry, 1979, vol. 32, # 12, p. 2713 - 2726
6-Benzothiazolol,2-(methylthio)-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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