5-IODO-6-METHYL-PYRIDIN-2-YLAMINE
- Product Name
- 5-IODO-6-METHYL-PYRIDIN-2-YLAMINE
- CAS No.
- 75073-11-9
- Chemical Name
- 5-IODO-6-METHYL-PYRIDIN-2-YLAMINE
- Synonyms
- ZERO/005167;AKOS BB-8251;ASISCHEM X26971;VITAS-BB TBB000516;6-AMINO-3-IODO-2-PICOLINE;2-Amino-5-iodo-6-picoline;5-IODO-6-METHYL-2-PYRIDINAMINE;5-IODO-6-METHYLPYRIDIN-2-AMINE;2-AMINO-5-IODO-6-METHYLPYRIDINE;6-Amino-3-iodo-2-methylpyridine
- CBNumber
- CB7129618
- Molecular Formula
- C6H7IN2
- Formula Weight
- 234.04
- MOL File
- 75073-11-9.mol
5-IODO-6-METHYL-PYRIDIN-2-YLAMINE Property
- Melting point:
- 99.9-100.1°C
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- solid
- Appearance
- White to off-white Solid
- Sensitive
- Light Sensitive
- CAS DataBase Reference
- 75073-11-9(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- ADE000318
- Product name
- 5-Iodo-6-methyl-pyridin-2-ylamine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $179
- Updated
- 2025/07/31
- Product number
- A576655
- Product name
- 2-Amino-5-iodo-6-methylpyridine
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 018252
- Product name
- 5-Iodo-6-methyl-pyridin-2-ylamine
- Packaging
- 1g
- Price
- $129
- Updated
- 2021/12/16
- Product number
- 3H32-H-83
- Product name
- 2-Amino-5-iodo-6-methylpyridine
- Purity
- 95.0%
- Packaging
- 1g
- Price
- $144
- Updated
- 2021/12/16
- Product number
- FA08614
- Product name
- 2-Amino-5-iodo-6-methylpyridine
- Packaging
- 10g
- Price
- $225
- Updated
- 2021/12/16
5-IODO-6-METHYL-PYRIDIN-2-YLAMINE Chemical Properties,Usage,Production
Synthesis
1824-81-3
75073-11-9
The general procedure for the synthesis of 2-amino-5-iodo-6-methylpyridine from 2-amino-6-methylpyridine is as follows: a mixture of 2-amino-6-methylpyridine (5.40 g), periodic acid (2.28 g), and iodine (5.00 g) was dissolved in a mixture of acetic acid (30 mL), water (6 mL), and sulfuric acid (0.9 mL), and heated to a reaction temperature of 80°C for 3 hr. . After the reaction was completed, the mixture was cooled to room temperature and slowly poured into 100 mL of 10% aqueous sodium bisulfite solution. The aqueous phase was extracted with ether (3 x 100 mL) and the organic phase was combined. The organic phase was washed sequentially with 10% sodium hydroxide solution, dried over anhydrous sodium sulfate, filtered and concentrated. Purification by column chromatography (eluent: ethyl acetate) gave a yellow liquid product. The liquid was further dried under a vacuum pump to induce crystallization to finally obtain 2-amino-5-iodo-6-methylpyridine (4.48 g, 38% yield). The physical properties of the product were as follows: 1H NMR (300 MHz, DMSO-d6) δ 7.60,6.09,6.05,2.38.
References
[1] Patent: WO2014/39484, 2014, A1. Location in patent: Page/Page column 50
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 25, p. 6383 - 6391
[3] Patent: US2002/7066, 2002, A1
[4] Tetrahedron Letters, 2001, vol. 42, # 23, p. 3795 - 3797
[5] Tetrahedron Letters, 2003, vol. 44, # 14, p. 2971 - 2973
5-IODO-6-METHYL-PYRIDIN-2-YLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-IODO-6-METHYL-PYRIDIN-2-YLAMINE manufacturers
- Product
- 5-IODO-6-METHYL-PYRIDIN-2-YLAMINE 75073-11-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-26
- Product
- 5-IODO-6-METHYL-PYRIDIN-2-YLAMINE 75073-11-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 100kg/week
- Release date
- 2019-08-05