1-Aziridinecarboxylicacid,1,1-dimethylethylester(9CI)
- Product Name
- 1-Aziridinecarboxylicacid,1,1-dimethylethylester(9CI)
- CAS No.
- 97308-23-1
- Chemical Name
- 1-Aziridinecarboxylicacid,1,1-dimethylethylester(9CI)
- Synonyms
- 1-Boc-aziridine;N-Boc-aziridine;N-(tert-butoxycarbonyl)aziridine;tert-butyl aziridine-1-carboxylate;1-Aziridinecarboxylicacid tert-butyl ester;tert-Butyl aziridine-1-carboxylate - [B8345];1-Aziridinecarboxylic acid, 1,1-diMethylethyl ester;1-Aziridinecarboxylicacid,1,1-dimethylethylester(9Cl);1-Aziridinecarboxylicacid,1.1-dimethylethylester(qci);1-Aziridinecarboxylicacid,1,1-dimethylethylester(9CI)
- CBNumber
- CB71298863
- Molecular Formula
- C7H13NO2
- Formula Weight
- 143.18
- MOL File
- 97308-23-1.mol
1-Aziridinecarboxylicacid,1,1-dimethylethylester(9CI) Property
- Boiling point:
- 174.8±9.0 °C(Predicted)
- Density
- 1.088±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- pka
- -3.23±0.20(Predicted)
- Appearance
- Colorless to light yellow Liquid
- InChI
- InChI=1S/C7H13NO2/c1-7(2,3)10-6(9)8-4-5-8/h4-5H2,1-3H3
- InChIKey
- VBYPJHLRWKGNAI-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CC1
N-Bromosuccinimide Price
- Product number
- B807042
- Product name
- N-(tert-Butoxycarbonyl)aziridine
- Packaging
- 100mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- B807042
- Product name
- N-(tert-Butoxycarbonyl)aziridine
- Packaging
- 500mg
- Price
- $440
- Updated
- 2021/12/16
- Product number
- B807042
- Product name
- N-(tert-Butoxycarbonyl)aziridine
- Packaging
- 1g
- Price
- $745
- Updated
- 2021/12/16
- Product number
- CS-0079678
- Product name
- tert-Butylaziridine-1-carboxylate
- Packaging
- 5g
- Price
- $808
- Updated
- 2021/12/16
- Product number
- CS-0079678
- Product name
- tert-Butylaziridine-1-carboxylate
- Packaging
- 1g
- Price
- $261
- Updated
- 2021/12/16
1-Aziridinecarboxylicacid,1,1-dimethylethylester(9CI) Chemical Properties,Usage,Production
Uses
N-(tert-Butoxycarbonyl)aziridine is a useful reagent for organic synthesis and other chemical processes. It is used as a reagent in the preparation of substituted indolines and carbazoles by benzyne-mediated cyclization-functionalization.
Synthesis
151-56-4
24424-99-5
97308-23-1
Example 47 Synthesis of N-Boc aziridine 166: To a solution of aziridine 165 (125 mg, 0.49 mmol) in dichloromethane (7 mL) was added triethylamine (70 μL), DMAP (catalytic amount), and di-tert-butyl dicarbonate (Boc anhydride, 113 mg, 0.52 mmol) in sequence. The reaction mixture was stirred at room temperature for 1 h and then concentrated under reduced pressure to remove the solvent. The residue was purified by fast column chromatography (eluent: hexane solution of 40% ethyl acetate) to afford 154 mg (88% yield) of the title compound, N-Boc aziridine 166, as a light colored oil.1H NMR (CDCl3, 300 MHz): δ 6.82 (m, 1H); 4.47 (br m, 1H); 4.23 (t, 2H, J = 4.7 Hz); 3.81 (t, 2H, J = 4.7 Hz); 3.75 (s, 3H); 3.00 (br d, 1H, J = 18.0 Hz); 2.90-2.85 (m, 2H); 2.65-2.55 (m, 1H); 2.10 (s, 3H); 1.44 (s, 9H).
References
[1] Chemical Communications, 1998, # 2, p. 253 - 254
[2] Patent: US6534037, 2003, B1
[3] Patent: US5952375, 1999, A
[4] Patent: US5763483, 1998, A
[5] Patent: US2004/53999, 2004, A1
1-Aziridinecarboxylicacid,1,1-dimethylethylester(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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