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desmethylazelastine

Product Name
desmethylazelastine
CAS No.
47491-38-3
Chemical Name
desmethylazelastine
Synonyms
Azelastin IMP;Demethylazelastine;Didehydromiltirone;Desmethylazelastine;Azelastine Impurity 6;N-Desmethyl Azelastine;desmethylazelastine Impurity;Azelastine Hydrochloride Impurity;N-Desmethyl Azelastine (1.0mg/ml in DMSO);N-Desmethyl Azelastine（Azelastine Impurity 20）
CBNumber
CB71328669
Molecular Formula
C21H22ClN3O
Formula Weight
367.87
MOL File
47491-38-3.mol
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desmethylazelastine Property

Melting point:
90-95°C
Boiling point:
544.1±60.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
10.49±0.40(Predicted)
color 
Pale Yellow to Light Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D290950
Product name
N-DesmethylAzelastine
Packaging
10mg
Price
$185
Updated
2021/12/16
TRC
Product number
D290950
Product name
N-DesmethylAzelastine
Packaging
100mg
Price
$1455
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD21239
Product name
N-Desmethyl azelastine
Packaging
10mg
Price
$1689.3
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD21239
Product name
N-Desmethyl azelastine
Packaging
25mg
Price
$3071.5
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
8951
Product name
N-DesmethylAzelastine
Packaging
12.5mg
Price
$3250
Updated
2021/12/16
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desmethylazelastine Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

The main phase I metabolites of Azelastine.

in vivo

1.19Pharmacokinetic parameters of desmethylazelastine after a single oral administration of 1.0 mg/kg azelastine hydrochloride in guinea pigs[1].
BloodLung
Cmax (ng/mL)[a]17.62863
Tmax (h)3.0-6.04.0-6.0
Tlag (h)0.250.39
AUC0-24 (ng?h/mL)[a]18028502
t1/2 (h)4.243.90
CL (L/h)0.213
Lung-blood ratio[b]146146
[a] For lung, the unit in grams (g) instead of milliliter (mL). [b] Mean value calculated from all time points.

desmethylazelastine Preparation Products And Raw materials

Raw materials

Preparation Products

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desmethylazelastine Suppliers

Canada 1 China 36 India 6 United Kingdom 1 United States 6 Global 50
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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+86-10-82967029
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021-50135380
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Artis Chemistry (Shanghai) Co. Ltd.
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China
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Clearsynth Labs Limited
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+91-22-26355700
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+91-22-26355701
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ChemStrong Scientific Co.,Ltd
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sales@chem-strong.com
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BOC Sciences
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United States
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Pharmacodia (Beijing) Co.,Ltd
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+86-400-851-9921
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+86-10-82826195
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China
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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Shenzhen Botel Biotechnology Co. Ltd.
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13316949107 13316968096
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1979313431@qq.com
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China
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47491-38-3, desmethylazelastineRelated Search:

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