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mexidol

Product Name
mexidol
CAS No.
127464-43-1
Chemical Name
mexidol
Synonyms
Emoxypine Succinate;ETHYLMETHYLHYDROXYPYRIDINE SUCCINATE;Mexifin;2-Ethyl-6-methyl-3-hydroxypyridine succinate;Mexidole;Emoxypine Succinate (Mexidol);mexidol;Mexiletine base;Mexidol succinate;Methoxyl west dol
CBNumber
CB71331340
Molecular Formula
C8H11NO.C4H6O4
Formula Weight
255.268
MOL File
127464-43-1.mol
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mexidol Property

Melting point:
119-120 °C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C8H11NO.C4H6O4/c1-3-7-8(10)5-4-6(2)9-7;5-3(6)1-2-4(7)8/h4-5,10H,3H2,1-2H3;1-2H2,(H,5,6)(H,7,8)
InChIKey
IKMNOGHPKNFPTK-UHFFFAOYSA-N
SMILES
C1(CC)N=C(C=CC=1O)C.C(C(=O)O)CC(=O)O
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Safety

HS Code 
2933.39.9200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1069
Product name
2-Ethyl-3-hydroxy-6-methylpyridine Succinate
Packaging
1G
Price
$171
Updated
2025/07/31
Matrix Scientific
Product number
177679
Product name
2-Ethyl-6-methyl-3-pyridinol succinate (salt)
Packaging
1g
Price
$10
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB165389
Product name
Butanedioic acid 2-ethyl-6-methyl-3-pyridinol (1:1)
Packaging
25g
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB165389
Product name
Butanedioic acid 2-ethyl-6-methyl-3-pyridinol (1:1)
Packaging
50g
Price
$80
Updated
2021/12/16
AK Scientific
Product number
X0082
Product name
EmoxypineSuccinate
Packaging
100mg
Price
$94
Updated
2021/12/16
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mexidol Chemical Properties,Usage,Production

Uses

The Chinese name of Mesidol is 2-ethyl-6methyl-3-hydroxypyridine succinic acid (Mexidox), 2-ethyl-6-methyl-3-hydroxypyridine succinate (emoxypine, product Name-MEXIDOL?, etc.) is widely used in medicine as an antioxidant and anti-hypoxic agent. Use 2-ethyl-6-methyl-3-hydroxypyridine succinate as a nootropic and anxiolytic, anti-ischemic and atherosclerotic, anti-angina, liver protection, antibacterial, etc.

Preparation

3.5 liters of ethanol, 1.2 kg of 2-ethyl-6-methyl-3-hydroxypyridine and 1.0 kg of succinic acid were added to the reactor. The reaction mass is heated to the boiling point of ethanol (78°C) and stirring is continued for 20 minutes until the components are completely dissolved. Then, keep the reaction mass in the reactor under stirring until the temperature reaches 20°C, cool to 5°C and keep at this temperature for 16 hours, stirring occasionally. The suspension is then stirred until the material is homogeneous, overloaded in a centrifuge and filtered. The precipitate of the succinate salt of 2-ethyl-6-methyl-3-hydroxypyridine was dried to constant weight in a vacuum oven at 45°C. The yield of the target product 2-ethyl-6-methyl-3-hydroxypyridine succinate (Mexitrad) was 89%.

in vivo

Emoxypine succinate (i.p.; 40 mg/kg; 1 time per day, 14 days) decreases the production of reactive oxygen species, mitochondrial transmembrane potential percentage of leukocyte and the percentage of FITC Annexin V- positive cells of leukocyte suspension[1].

Animal Model:Rats[1]
Dosage:40 mg/kg
Administration:Intraperitoneal, 1 time per day, 14 days
Result:Significantly increased the percentage of Annexin V-positive cells, reduced the apoptotic percentage of white blood cells and decreased the production of reactive oxygen species by leukocytes.

mexidol Preparation Products And Raw materials

Raw materials

Preparation Products

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mexidol Suppliers

Americas 1 China 166 Europe 1 India 8 Japan 1 Russia 1 Switzerland 2 United Kingdom 1 United States 10 Global 191
TCI (Shanghai) Development Co., Ltd.
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View Lastest Price from mexidol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Mexidole 127464-43-1
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
10 TONS
Release date
2021-06-19
Wuhan Biocar Pharmacy CO.,Ltd.
Product
Mexidole 127464-43-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
800kg
Release date
2025-02-21
Shaanxi Dideu Medichem Co. Ltd
Product
mexidol 127464-43-1
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-12

127464-43-1, mexidolRelated Search:

Ganciclovir Exemestane Diltiazem hydrochloride Acyclovir 2-ETHYL-3-HYDROXY-6-METHYLPYRIDINE mexidol 2,6-DIMETHYL-3-HYDROXYPYRIDINE 3-Hydroxy-6-methylpyridine

  • mexidol
  • 2-Ethyl-6-methyl-3-pyridinol butanoate (1:1)
  • 2-Ethyl-6-methyl-3-hydroxypyridine succinate
  • Butanedioic acid 2-ethyl-6-methyl-3-pyridinol (1:1)
  • Mexidole (2-ethyl-6-Methyl-3-hydroxypyridine succinate)
  • 2-Ethyl-6-Methylpyridin-3-ol succinate
  • 2-ethyl-6-Methyl-3-hydroxypyridine succinate (Mexidole)
  • 2-Ethyl-6-Methyl-3-pyridinol butanoate
  • 2-Ethyl-3-hydroxy-6-methylpyridine Succinate
  • 2-Ethyl-6-methyl-3-pyridinol succinate (salt)
  • Mexidole
  • Mexidol succinate
  • Emoxypine Succinate
  • 2-Ethyl-3-hydroxy-6-methylpyridineSuccinate&gt
  • Methoxyl west dol
  • ETHYLMETHYLHYDROXYPYRIDINE SUCCINATE
  • mexidol ISO 9001：2015 REACH
  • Mexiletine base
  • High purity CAS 127464-43-1 mexidol in stock
  • Mexifin
  • Emoxypine Succinate (Mexidol)
  • Emoxypine Succinate (Mexifin)
  • Mexidole(2-ethyl-6-ChemicalbookMethyl-3-hydroxypyridinesuccinate)
  • 2-Ethyl-6-methylpyridine-3-ol succinate
  • Emoxypine Succinate, 10 mM in DMSO
  • Pyridoxine Impurity 83 Succinic acid
  • 127464-43-1
  • C8H11NOC4H6O4