ChemicalBook > CAS DataBase List > CGS 25155
CGS 25155
- Product Name
- CGS 25155
- CAS No.
- 150126-87-7
- Chemical Name
- CGS 25155
- Synonyms
- CGS 25155;L-Proline, 1-[[(2S,9R)-9-[(acetylthio)methyl]decahydro-10-oxo-2-azecinyl]carbonyl]-4-hydroxy-, phenylmethyl ester, (4R)-
- CBNumber
- CB71335803
- Molecular Formula
- C25H34N2O6S
- Formula Weight
- 490.61
- MOL File
- 150126-87-7.mol
More
Less
CGS 25155 Property
- Boiling point:
- 725.0±60.0 °C(Predicted)
- Density
- 1.234±0.06 g/cm3(Predicted)
- pka
- 14.01±0.40(Predicted)
More
Less
CGS 25155 Chemical Properties,Usage,Production
Description
Cgs 25155 is an orally active NEP 24.11 inhibitor.
Uses
CGS25155 is an orally active neutral endopeptidase 24.11 (NEP 24.11) inhibitor with an IC50 of 3 nM. CGS25155 can slow down the degradation of the cardiac hormone atrial natriuretic peptide (ANP) and exhibits antihypertensive activity in the DOCA-salt induced rat hypertension model. CGS25155 can be used in cardiovascular disease research[1].
References
[1] MacPherson LJ, et al. Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor. J Med Chem. 1993 Nov 26;36(24):3821-8. DOI:10.1021/jm00076a009
CGS 25155 Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
CGS 25155 Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 29257
- Advantage
- 58